Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15001297 | 0.87 | TOP2A (0.41) | TOP2AHPGDTAS1R3TAS1R1FPR1 | |
| SCHEMBL14802308 | 0.87 | TOP2A (0.41) | TOP2AHPGDTAS1R3TAS1R1FPR1 | |
| SCHEMBL12345944 | 0.87 | TOP2A (0.41) | TOP2AHPGDTAS1R3TAS1R1FPR1 | |
| SCHEMBL15001286 | 0.87 | TOP2A (0.41) | TOP2AHPGDTAS1R3TAS1R1FPR1 | |
| SCHEMBL15001293 | 0.87 | TOP2A (0.41) | TOP2AHPGDTAS1R3TAS1R1FPR1 | |
| SCHEMBL15001287 | 0.86 | TOP2A (0.40) | TOP2AHPGDTAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL15001280 | 0.83 | L3MBTL1 (0.40) | TOP2AESR1HPGDTAS1R3TAS1R1 | |
| SCHEMBL14580020 | 0.82 | ESR1 (0.49) | ESR1ESR2HPGDKDM4ETDP1 | |
| SCHEMBL12346028 | 0.81 | SLC6A2 (0.44) | TOP2AHPGDAKR1C3TAS1R3TAS1R1 | |
| SCHEMBL12345973 | 0.80 | KMT2A (0.40) | TOP2AMEN1KMT2AL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404414-B2 | Electrophotographic photoconductor and manufacturing method thereof | FUJI ELECTRIC CO., LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110189603-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF | FUJI ELECTRIC SYSTEMS CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |