Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GOT1 | P17174 | 6/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27923240 | 0.70 | ADRB1 (0.51) | ADRB1HTR6AHRGAADRD2 | |
| SCHEMBL16719806 | 0.69 | ADRB1 (0.54) | ADRB1HTR6AHRGAADRD2 | |
| SCHEMBL30557150 | 0.67 | ADRB1 (0.51) | ADRB1HTR6AHRGAADRD2 | |
| SCHEMBL20581870 | 0.67 | ADRB1 (0.75) | ADRB1HTR6GAADRD2DRD4 | |
| SCHEMBL9703840 | 0.67 | ADRB1 (0.69) | ADRB1HTR6GAADRD2DRD4 | |
| SCHEMBL476853 | 0.67 | AHR (0.42) | ADRB1HTR6AHRGAADRD2 | |
| SCHEMBL4306478 | 0.67 | ADRB1 (0.69) | ADRB1HTR6GAADRD2DRD4 | |
| SCHEMBL29374726 | 0.67 | AHR (0.42) | ADRB1HTR6AHRGAADRD2 | |
| SCHEMBL29941044 | 0.67 | ADRB1 (0.69) | ADRB1HTR6GAADRD2DRD4 | |
| SCHEMBL488782 | 0.67 | AHR (0.42) | ADRB1HTR6AHRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201599-A1 | CDK Modulators | EXELIXIS, INC. (US) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201599-A1 | CDK Modulators | CDK3, CDK1, CDKL1 | ADRB1 2303/4885HTR6 3348/4885AHR 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.