Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13788784 | 0.85 | TSHR (0.40) | TSHRNPY5RALDH1A1MAPTGAA | |
| SCHEMBL12355529 | 0.84 | TSHR (0.39) | TSHRNPY5RALDH1A1MAPTGAA | |
| SCHEMBL14586630 | 0.80 | HTR2A (0.44) | TSHRALDH1A1MAPTHTTESR1 | |
| SCHEMBL5583584 | 0.78 | TDP1 (0.44) | TSHRALDH1A1MAPTGAAHPGD | |
| SCHEMBL13884320 | 0.73 | PTPN1 (0.41) | TSHRALDH1A1MAPTGAAALOX12 | |
| SCHEMBL13064207 | 0.71 | TSHR (0.52) | TSHRHTTRORC | |
| SCHEMBL13019895 | 0.71 | TSHR (0.47) | TSHRHPGDHTTRORCLMNA | |
| SCHEMBL9233877 | 0.70 | PGR (0.52) | TSHRNPY5RALDH1A1MAPTALOX12 | |
| SCHEMBL18812295 | 0.70 | TSHR (0.50) | TSHRALDH1A1MAPTGAAALOX12 | |
| SCHEMBL13064414 | 0.68 | TSHR (0.52) | TSHRALDH1A1MAPTHTTRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003799-B2 | For agriculture | BAYER SAS (FR) | 2011-08-23 | — | — | US | disclosed |
| US-8003799-B2 | For agriculture | BAYER SAS (FR) | 2011-08-23 | — | — | US | disclosed |
| US-7560565-B2 | Method for preparing derivatives of 3-hydroxypicolinic acid | BAYER CROPSCIENCE SA (FR) | 2009-07-14 | — | — | US | disclosed |