Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14586630 | 0.85 | HTR2A (0.44) | TDP1TSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13788784 | 0.81 | TSHR (0.40) | TSHRALDH1A1MAPTGAAHPGD | |
| SCHEMBL12355529 | 0.80 | TSHR (0.39) | TSHRALDH1A1MAPTGAAHPGD | |
| SCHEMBL12347495 | 0.78 | TSHR (0.38) | TSHRALDH1A1MAPTGAAHPGD | |
| SCHEMBL17660080 | 0.78 | TDP1 (0.46) | TDP1TSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13064207 | 0.76 | TSHR (0.52) | TSHRCYP3A4TP53 | |
| SCHEMBL6558453 | 0.75 | ALDH1A1 (0.54) | TDP1TSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29875775 | 0.73 | NCOA1 (0.44) | TDP1TSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28823511 | 0.73 | NCOA1 (0.44) | TDP1TSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19236577 | 0.72 | TSHR (0.52) | TSHRALDH1A1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |