SCHEMBL123483

SCHEMBL123483

O=C(Oc1ccc(Cl)cc1Cl)Oc1ccc(Cl)cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
TTR P02766 3/20 0.52
MAPT P10636 2/20 0.52
HPGD P15428 2/20 0.52
NR1I2 O75469 1/20 0.52
LMNA P02545 1/20 0.52
PGR P06401 1/20 0.52
HSP90AA1 P07900 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
HSPA5 P11021 1/20 0.52
CBR1 P16152 1/20 0.52
TBXA2R P21731 1/20 0.52
SLC6A2 P23975 1/20 0.52
AGTR1 P30556 1/20 0.52
SLC6A3 Q01959 1/20 0.52
TSHR P16473 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TP53 P04637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30225290 1.00 TDP1 (0.56) TDP1KMT2AMEN1TTRMAPT
SCHEMBL618918 0.87 TDP1 (0.56) TDP1KMT2AMEN1TTRMAPT
SCHEMBL31572520 0.87 TDP1 (0.56) TDP1KMT2AMEN1TTRMAPT
SCHEMBL3129615 0.85 TDP1 (0.59) TDP1KMT2AMEN1TTRMAPT
SCHEMBL5147669 0.85 TDP1 (0.55) TDP1KMT2AMEN1TTRMAPT
SCHEMBL3129607 0.85 TDP1 (0.55) TDP1KMT2AMEN1TTRMAPT
SCHEMBL8861735 0.83 KMT2A (0.57) TDP1KMT2AMEN1TTRMAPT
SCHEMBL18697333 0.83 TDP1 (0.53) TDP1KMT2AMEN1TTRMAPT
Hydrochloric Acid SCHEMBL11842989 0.83 TDP1 (0.58) TDP1KMT2AMEN1TTRMAPT
SCHEMBL134715 0.83 KMT2A (0.57) TDP1KMT2AMEN1TTRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344240-A Preparation method of 2, 4-dichloro-5-bromophenol 中国科学技术大学 2024-07-16 CN claimed
CN-117466714-A Preparation method of 2, 4-dichloro-5-halogenated phenol 中国科学技术大学 2024-01-30 CN claimed
CN-108373415-B Preparation method of di (2, 4-dichloro-5-nitrophenyl) carbonate 常州大学 2020-11-10 CN claimed
US-7893274-B2 Process for producing amino acid N-carboxyanhydride JSR CORPORATION (JP) 2011-02-22 US claimed
EP-1896520-A2 POLYMERIZATION PROCESS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2008-03-12 EP claimed
US-20070043185-A1 Polymerization process E. I. DU PONT DE NEMOURS AND COMPANY 2007-02-22 US claimed
WO-2006133369-A2 POLYMERIZATION PROCESS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-12-14 WO claimed
EP-1399498-B1 MELT POLYCARBONATE CATALYST SYSTEMS GEN ELECTRIC (US) 2006-06-21 EP claimed
EP-1551900-A1 POLYCARBONATE COPOLYMERS AND METHODS FOR PRODUCING THE POLYCARBONATE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2005-07-13 EP claimed
EP-1353971-B1 MELT POLYCARBONATE CATALYST SYSTEMS GEN ELECTRIC (US) 2005-05-11 EP claimed
US-6376640-B1 USING CESIUM POLYMERIZATION CATALYST GENERAL ELECTRIC COMPANY 2002-04-23 US claimed
US-6323304-B1 CONTACTING A DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE PRESENCE OF CATALYST COMPRISED OF ALKALI OR ALKALINE EARTH METAL-TRANSITION METAL FLUORIDE COMPOUND AND IN PRESENCE OF COCATALYST GENERAL ELECTRIC COMPANY 2001-11-27 US claimed
US-6323303-B1 POLYMERIZING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE PRESENCE OF A RUTHENIUM (II) OR RUTHENIUM (III) COMPOUND OR COMPLEX; OPTIONALLY IN PRESENCE OF A TETRAALKYL AMMONIUM OR TETRAALKYL PHOSPHONIUM SALT GENERAL ELECTRIC COMPANY 2001-11-27 US claimed
US-6303737-B1 POLYCONDENSATION CATALYSTS WHICH ARE SALTS OF CERTAIN PHENANTHROLINE COMPOUNDS; EXCELLENT POLYMERIZATION RATES; REDUCING THE LEVEL OF BRANCHING SIDE REACTION, I.E., FORMATION OF FRIES PRODUCT GENERAL ELECTRIC COMPANY 2001-10-16 US claimed
US-6291631-B1 CONTACTING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE POLYMERIZATION CATALYST UNDER POLYCARBONATE MELT POLYMERIZATION CONDITIONS GENERAL ELECTRIC COMPANY 2001-09-18 US claimed
US-5391693-A Copolymerization of aromatic diol and 9,9-bis(4-hydroxyphenyl) fluorene derivative in presence of phosgene or derivatives in inert solvent in presence of potassium hydroxide IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-02-21 US claimed
US-5168112-A Process for the preparation of a polycarbonate with piperidinyl pyridine catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-01 US claimed
EP-0492003-A1 Process for the preparation of polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1992-07-01 EP claimed
US-5025083-A Process for preparation of polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1991-06-18 US claimed
EP-0382250-A2 Process for preparation of polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1990-08-16 EP claimed