SCHEMBL18697333

SCHEMBL18697333

O=C(F)Oc1ccc(Cl)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.53
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
TTR P02766 3/20 0.48
MAPT P10636 2/20 0.48
HPGD P15428 2/20 0.48
NR1I2 O75469 1/20 0.48
LMNA P02545 1/20 0.48
PGR P06401 1/20 0.48
HSP90AA1 P07900 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
HSPA5 P11021 1/20 0.48
CBR1 P16152 1/20 0.48
TBXA2R P21731 1/20 0.48
SLC6A2 P23975 1/20 0.48
AGTR1 P30556 1/20 0.48
SLC6A3 Q01959 1/20 0.48
MRGPRX4 Q96LA9 4/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL618918 0.83 TDP1 (0.56) TDP1KMT2AMEN1TTRMAPT
SCHEMBL30225290 0.83 TDP1 (0.56) TDP1KMT2AMEN1TTRMAPT
SCHEMBL31572520 0.83 TDP1 (0.56) TDP1KMT2AMEN1TTRMAPT
SCHEMBL123483 0.83 TDP1 (0.56) TDP1KMT2AMEN1TTRMAPT
SCHEMBL3129615 0.82 TDP1 (0.59) TDP1KMT2AMEN1TTRMAPT
SCHEMBL5147669 0.82 TDP1 (0.55) TDP1KMT2AMEN1TTRMAPT
SCHEMBL3129607 0.82 TDP1 (0.55) TDP1KMT2AMEN1TTRMAPT
SCHEMBL8861735 0.80 KMT2A (0.57) TDP1KMT2AMEN1TTRMAPT
Hydrochloric Acid SCHEMBL11842989 0.80 TDP1 (0.58) TDP1KMT2AMEN1TTRMAPT
SCHEMBL134715 0.80 KMT2A (0.57) TDP1KMT2AMEN1TTRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194664-A1 NONAQUEOUS ELECTROLYTE AND ELECTRICITY STORING DEVICE IN WHICH SAME IS USED MU IONIC SOLUTIONS CORPORATION (JP) 2017-07-06 US disclosed
US-20170194664-A1 NONAQUEOUS ELECTROLYTE AND ELECTRICITY STORING DEVICE IN WHICH SAME IS USED MU IONIC SOLUTIONS CORPORATION (JP) 2017-07-06 US disclosed
EP-3151326-A1 NONAQUEOUS ELECTROLYTE AND ELECTRICITY-STORING DEVICE IN WHICH SAME IS USED Ube Industries, Ltd. (JP) 2017-04-05 EP disclosed