Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | CBR1 | P16152 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123483 | 0.85 | TDP1 (0.56) | TDP1KMT2AMEN1TTRMAPT | |
| SCHEMBL30225290 | 0.85 | TDP1 (0.56) | TDP1KMT2AMEN1TTRMAPT | |
| SCHEMBL31572520 | 0.85 | TDP1 (0.56) | TDP1KMT2AMEN1TTRMAPT | |
| SCHEMBL618918 | 0.85 | TDP1 (0.56) | TDP1KMT2AMEN1TTRMAPT | |
| SCHEMBL3129607 | 0.83 | TDP1 (0.55) | TDP1KMT2AMEN1TTRMAPT | |
| SCHEMBL3129615 | 0.83 | TDP1 (0.59) | TDP1KMT2AMEN1TTRMAPT | |
| SCHEMBL11717445 | 0.83 | ALDH1A1 (0.45) | TDP1KMT2AMEN1LMNATSHR | |
| SCHEMBL134715 | 0.82 | KMT2A (0.57) | TDP1KMT2AMEN1TTRMAPT | |
| SCHEMBL18697333 | 0.82 | TDP1 (0.53) | TDP1KMT2AMEN1TTRMAPT | |
| Hydrochloric Acid SCHEMBL11842989 | 0.82 | TDP1 (0.58) | TDP1KMT2AMEN1TTRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276017-A1 | Thiadiazoline Derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1632484-A1 | THIADIAZOLINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-03-08 | — | — | EP | disclosed |
| US-20020082254-A1 | Compounds for treating disorders where a decreased level of plasma FFA is desired | NOVO NORDISK A/S (DK) | 2002-06-27 | — | — | US | disclosed |
| WO-2001087843-A1 | COMPOUNDS FOR TREATING DISORDERS WHERE A DECREASED LEVEL OF PLASMA FFA IS DESIRED | NOVO NORDISK A/S (DK) | 2001-11-22 | — | — | WO | disclosed |
| US-5600025-A | CHEMICAL INTERMEDIATES FOR NONWAXY FUEL AND LUBRICANT ADDITIVES CONTAINING ALKYLPHENYL POLY(OXYPROPYLENE) AMINOCARBAMATES; ANTIDEPOSIT AGENTS | CHEVRON CHEMICAL COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| EP-0404876-B1 | LONG-CHAIN ALIPHATIC HYDROCARBYL AMINE ADDITIVES HAVING AN OXY-CARBONYL CONNECTING GROUP | CHEVRON RES & TECH (US) | 1995-02-15 | — | — | EP | disclosed |
| EP-0419488-A4 | LUBRICATING OIL COMPOSITIONS AND FUEL COMPOSITIONS CONTAINING SUBSTANTIALLY STRAIGHT CHAIN PINWHEEL ALKYLPHENYL POLY(OXYPROPYLENE) AMINOCARBAMATES | CHEVRON RES (US) | 1994-11-23 | — | — | EP | disclosed |
| US-5364546-A | Dispersants, improved compatibility | CHEVRON RESEARCH COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| US-5322529-A | Liquid additive; internal combustion engines | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1994-06-21 | — | — | US | disclosed |
| US-5312965-A | Dispersants | CHEVRON RESEARCH COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| EP-0396573-A4 | FUEL COMPOSITIONS AND LUBRICATING OIL COMPOSITIONS CONTAINING VERY LONG CHAIN ALKYLPHENYL POLY(OXYALKYLENE) AMINOCARBAMATES | — | 1990-11-28 | — | — | EP | disclosed |
| EP-0396573-A1 | FUEL COMPOSITIONS AND LUBRICATING OIL COMPOSITIONS CONTAINING VERY LONG CHAIN ALKYLPHENYL POLY(OXYALKYLENE) AMINOCARBAMATES. | CHEVRON RES (US) | 1990-11-14 | — | — | EP | disclosed |
| WO-1990007564-A1 | LUBRICATING OIL COMPOSITIONS AND FUEL COMPOSITIONS CONTAINING SUBSTANTIALLY STRAIGHT CHAIN PINWHEEL ALKYLPHENYL POLY(OXYPROPYLENE) AMINOCARBAMATES | CHEVRON RESEARCH COMPANY (US) | 1990-07-12 | — | — | WO | disclosed |
| US-4933485-A | DISPERSANT ADDITIVES POSSESSING IMPROVED COMPATIBILITY | CHEVRON RESEARCH COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| WO-1990004582-A1 | FUEL COMPOSITIONS AND LUBRICATING OIL COMPOSITIONS CONTAINING VERY LONG CHAIN ALKYLPHENYL POLY(OXYALKYLENE) AMINOCARBAMATES | CHEVRON RESEARCH COMPANY (US) | 1990-05-03 | — | — | WO | disclosed |
| WO-1990002785-A1 | LONG-CHAIN ALIPHATIC HYDROCARBYL AMINE ADDITIVES HAVING AN OXY-CARBONYL CONNECTING GROUP | CHEVRON RESEARCH COMPANY (US) | 1990-03-22 | — | — | WO | disclosed |
| US-4881945-A | LUBRICATING OIL COMPATIBILITY | CHEVRON RESEARCH COMPANY (US) | 1989-11-21 | — | — | US | disclosed |
| EP-0297996-A2 | Lubricating oil compositions and fuel compositions containing substantially straight chain alkylphenyl poly(oxypropylene) aminocarbamates | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1989-01-04 | — | — | EP | disclosed |
| US-4376731-A | 2-NITRILES THEREOF | BOEHRINGER MANNHEIM GMBH (DE) | 1983-03-15 | — | — | US | disclosed |
| US-3986973-A | CYANOFORMATES AND CYANOFORMAMIDES AS BLEACH ACTIVATORS | AMERICAN CYANAMID COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276017-A1 | Thiadiazoline Derivative | BRD7, NR3C2, NR5A2 | TDP1 3187/4885KMT2A 3066/4885MEN1 2331/4885 |
| US-20020082254-A1 | Compounds for treating disorders where a decreased level of plasma FFA is desired | FABP1, FFAR2, FFAR1 | TDP1 4063/4885KMT2A 4207/4885MEN1 2075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.