Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18216657 | 0.83 | MAP4K4 (0.56) | PIK3CDMAP4K4CYP1A2KCNH2MINK1 | |
| SCHEMBL1256207 | 0.81 | CYP3A4 (0.63) | PIK3CDMAP4K4CYP1A2KCNH2MINK1 | |
| SCHEMBL15889943 | 0.79 | MAP4K4 (0.51) | PIK3CDMAP4K4NOS3NOS2MKNK1 | |
| SCHEMBL17027854 | 0.78 | PIK3CD (0.51) | PIK3CDMAP4K4CYP1A2KCNH2MINK1 | |
| SCHEMBL12259927 | 0.78 | CYP3A4 (0.56) | CYP3A4KMO | |
| SCHEMBL17805340 | 0.77 | PIK3CD (0.50) | PIK3CDMAP4K4CYP1A2KCNH2MINK1 | |
| SCHEMBL4495649 | 0.76 | MAP4K4 (0.54) | PIK3CDMAP4K4CYP1A2KCNH2MINK1 | |
| SCHEMBL29740321 | 0.76 | PIK3CD (0.73) | PIK3CDMAP4K4CYP1A2KCNH2MINK1 | |
| SCHEMBL1257460 | 0.76 | PIK3CD (0.73) | PIK3CDMAP4K4CYP1A2KCNH2MINK1 | |
| SCHEMBL22198981 | 0.75 | MAP4K4 (0.51) | PIK3CDMAP4K4CYP1A2KCNH2MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097300-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA, INC. (US) | 2011-08-11 | — | — | WO | disclosed |