Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 8/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761291 | 0.78 | FEN1 (0.55) | FEN1ALOX5APMAP4K4PIK3CDMKNK1 | |
| SCHEMBL23044427 | 0.78 | MAP4K4 (0.51) | FEN1ALOX5APNOS3NOS2MAP4K4 | |
| SCHEMBL3813230 | 0.78 | ABL1 (0.63) | NOS3NOS2PIK3CDMKNK1MKNK2 | |
| SCHEMBL16681201 | 0.78 | ABL1 (0.48) | NOS3NOS2MAP4K4PIK3CDMKNK1 | |
| SCHEMBL15730148 | 0.78 | MKNK1 (0.57) | FEN1ALOX5APNOS3NOS2MAP4K4 | |
| SCHEMBL29690149 | 0.78 | MAP4K4 (0.51) | FEN1ALOX5APNOS3NOS2MAP4K4 | |
| SCHEMBL16681203 | 0.77 | NOS3 (0.52) | FEN1NOS3NOS2MAP4K4PIK3CD | |
| SCHEMBL3813235 | 0.77 | NOS3 (0.52) | FEN1NOS3NOS2MAP4K4PIK3CD | |
| SCHEMBL17805365 | 0.77 | NOS3 (0.47) | FEN1NOS3NOS2MAP4K4PIK3CD | |
| SCHEMBL4933140 | 0.77 | MEN1 (0.47) | CTSDBACE1FEN1ALOX5APLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105992767-A | Wnt pathway modulators | 新加坡科技研究局 | 2016-10-05 | — | — | CN | disclosed |
| WO-2011097300-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA, INC. (US) | 2011-08-11 | — | — | WO | disclosed |