SCHEMBL12349448

SCHEMBL12349448

c1ccc(-n2c(-c3ccc(-c4cccc5c4oc4ccccc45)cc3-c3cccc4ccccc34)nc3ccccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
RECQL P46063 1/20 0.42
RAB9A P51151 2/20 0.37
ESR1 P03372 3/20 0.37
ESR2 Q92731 3/20 0.37
PRKACA P17612 1/20 0.36
RPS6KB1 P23443 1/20 0.36
GSK3B P49841 1/20 0.36
ROCK1 Q13464 1/20 0.36
FLT3 P36888 1/20 0.36
GGPS1 O95749 1/20 0.36
PRKDC P78527 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
HDAC1 Q13547 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
GRIA1 P42261 1/20 0.34
CACNG8 Q8WXS5 1/20 0.34
CACNG2 Q9Y698 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12349418 0.96 ALOX5 (0.43) ALOX5RECQLRAB9AESR1ESR2
SCHEMBL12349416 0.93 ALOX5 (0.44) ALOX5RECQLRAB9AESR1ESR2
SCHEMBL12349449 0.93 ALOX5 (0.46) ALOX5RECQLRAB9AESR1ESR2
SCHEMBL12349359 0.92 ALOX5 (0.45) ALOX5RECQLRAB9AESR1ESR2
SCHEMBL12349414 0.91 ALOX5 (0.42) ALOX5RECQLRAB9AESR1ESR2
SCHEMBL12349424 0.90 ALOX5 (0.43) ALOX5RECQLRAB9AESR1ESR2
SCHEMBL12349193 0.88 RECQL (0.46) ALOX5RECQLRAB9AESR1ESR2
SCHEMBL1994838 0.88 ESR1 (0.48) ALOX5RECQLRAB9AESR1ESR2
SCHEMBL12568069 0.87 RECQL (0.41) ALOX5RECQLRAB9AESR1ESR2
SCHEMBL12349235 0.87 ALOX5 (0.40) ALOX5RECQLRAB9AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2662369-B1 Benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2015-09-23 EP disclosed
EP-2662369-A1 benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-11-13 EP disclosed
EP-2354135-B1 Benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2013-09-18 EP disclosed
US-8354542-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-15 US disclosed
US-8354542-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-15 US disclosed
EP-2354135-A1 benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-08-10 EP disclosed
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device CCNE2, CCNE1, CCNT1 ALOX5 1235/4885RECQL 706/4885RAB9A 2532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.