Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.76 |
| ▸ | RAB9A | P51151 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15382775 | 0.92 | NPC1 (0.70) | NPC1RAB9AKDM4EMAPTADRA1B | |
| SCHEMBL14646318 | 0.89 | NPC1 (0.77) | NPC1RAB9AKDM4EMAPTADRA1B | |
| SCHEMBL22627455 | 0.88 | KDM4E (0.69) | NPC1RAB9AKDM4EMAPTADRA1B | |
| SCHEMBL15382821 | 0.87 | RAB9A (0.63) | NPC1RAB9AKDM4EMAPTADRA1B | |
| SCHEMBL15382772 | 0.87 | RAB9A (0.63) | NPC1RAB9AKDM4EMAPTADRA1B | |
| SCHEMBL971875 | 0.86 | NPC1 (1.00) | NPC1RAB9AKDM4EMAPTADRA1B | |
| SCHEMBL22627410 | 0.86 | NPC1 (0.72) | NPC1RAB9AKDM4EMAPTADRA1B | |
| SCHEMBL10655871 | 0.86 | NPC1 (0.72) | NPC1RAB9AKDM4EMAPTADRA1B | |
| SCHEMBL13133694 | 0.86 | NPC1 (0.67) | NPC1RAB9AKDM4EMAPTADRA1B | |
| SCHEMBL22627500 | 0.84 | NPC1 (0.68) | NPC1RAB9AKDM4EMAPTADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020221380-A1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) | 2020-11-05 | — | — | WO | disclosed |
| EP-3693372-A1 | BENZOFURO[3',2':4,5]IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN ORGANIC LIGHT-EMITTING DEVICES (OLEDS) | Samsung Display Co., Ltd. (KR) | 2020-08-12 | — | — | EP | disclosed |
| WO-2020029980-A1 | SMAD3 INHIBITORS | MOEXA PHARMACEUTICALS LIMITED (CN) | 2020-02-13 | — | — | WO | disclosed |
| WO-2019190184-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2019-10-03 | — | — | WO | disclosed |
| US-10032994-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-07-24 | — | — | US | disclosed |
| US-20180097186-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-04-05 | — | — | US | disclosed |
| US-20180076392-A1 | CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-03-15 | — | — | US | disclosed |
| US-9887244-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-02-06 | — | — | US | disclosed |
| US-9822118-B2 | Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2017-11-21 | — | — | US | disclosed |
| US-9818960-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-11-14 | — | — | US | disclosed |
| US-20070179297-A1 | Chemical compounds | ASTRAZENECA AB, A SWEDEN CORPORATION | 2007-08-02 | — | — | US | disclosed |
| US-7244740-B2 | Imidazo-pyridine derivatives for use in the treatment of herpes viral infection | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-17 | — | — | US | disclosed |
| US-7238811-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2007-07-03 | — | — | US | disclosed |
| US-7238811-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2007-07-03 | — | — | US | disclosed |
| US-20070135451-A1 | Imidazo[1,2-a]Pyridine Derivatives for Treatment Of Herpes Viral Infections | GUDMUNDSSON KRISTJAN S | 2007-06-14 | — | — | US | disclosed |
| US-20070120111-A1 | Organic thin film transistor | IDEMITSU KOSAN CO., LTD. (JP) | 2007-05-31 | — | — | US | disclosed |
| US-20070120111-A1 | Organic thin film transistor | IDEMITSU KOSAN CO., LTD. (JP) | 2007-05-31 | — | — | US | disclosed |
| US-7186714-B2 | Imidazo[1,2-α]pyridine derivatives for the prophylaxis and treatment of herpes viral infections | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7179922-B2 | 4-Phenyloxypiperidionopiperidine compounds as antiinflammatory agents; autoimmune diseases; rheumatic diseases; cardiovascular disorders | ASTRAZENECA AB (SE) | 2007-02-20 | — | — | US | disclosed |
| US-7179922-B2 | 4-Phenyloxypiperidionopiperidine compounds as antiinflammatory agents; autoimmune diseases; rheumatic diseases; cardiovascular disorders | ASTRAZENECA AB (SE) | 2007-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180076392-A1 | CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME | MCM7, CCNB2, CCNE2 | NPC1 3377/4885RAB9A 2991/4885KDM4E 4244/4885 |
| US-20180097186-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | C1S, C1R, C9 | NPC1 2851/4885RAB9A 4242/4885KDM4E 3724/4885 |
| US-20070135451-A1 | Imidazo[1,2-a]Pyridine Derivatives for Treatment Of Herpes Viral Infections | IRF3, IFNAR1, IL2 | NPC1 1118/4885RAB9A 1481/4885KDM4E 478/4885 |
| US-20070179297-A1 | Chemical compounds | CCR3, CCR1, CCR4 | NPC1 887/4885RAB9A 2189/4885KDM4E 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.