Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1235006 | 1.00 | MTNR1A (0.46) | MTNR1AMTNR1BDRD3DRD2HRH2 | |
| SCHEMBL174754 | 0.85 | MTNR1A (0.47) | MTNR1AMTNR1BDRD3DRD2HRH2 | |
| SCHEMBL1031127 | 0.84 | DRD3 (0.62) | DRD3DRD2HRH2ADRA2ADRD4 | |
| SCHEMBL1031126 | 0.84 | DRD3 (0.62) | DRD3DRD2HRH2ADRA2ADRD4 | |
| SCHEMBL8204692 | 0.84 | DRD3 (0.62) | DRD3DRD2HRH2ADRA2ADRD4 | |
| Hydrochloric Acid SCHEMBL27632996 | 0.83 | ADRA2A (0.63) | DRD3DRD2HRH2ADRA2ADRD4 | |
| SCHEMBL28424830 | 0.83 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2GSK3BCSNK2A1 | |
| Bromide SCHEMBL4103965 | 0.83 | DRD3 (0.61) | DRD3DRD2HRH2ADRA2ADRD4 | |
| SCHEMBL17165294 | 0.82 | DRD3 (0.60) | DRD3DRD2HRH2ADRA2ADRD4 | |
| SCHEMBL28373665 | 0.79 | DRD3 (0.56) | DRD3DRD2HRH2ADRA2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011021214-A2 | IMPROVED PROCESS FOR THE PREPARATION OF (S)-2-AMINO-4,5,6,7-TETRAHYDRO-6 - (PROPYLAMINO) BENZOTHIAZOLE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | MSN LABORATORIES LIMITED (IN) | 2011-02-24 | — | — | WO | disclosed |