Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCTP | Q9UKL6 | 10/20 | 1.00 |
| ▸ | STARD10 | Q9Y365 | 5/20 | 1.00 |
| ▸ | STARD7 | Q9NQZ5 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1234435 | 0.90 | PCTP (1.00) | PCTPSTARD10STARD7MEN1GAA | |
| SCHEMBL1233504 | 0.88 | PCTP (1.00) | PCTPSTARD10STARD7MEN1GAA | |
| SCHEMBL1235845 | 0.82 | PCTP (1.00) | PCTPSTARD10STARD7MEN1GAA | |
| SCHEMBL13470343 | 0.80 | PCTP (0.85) | PCTPSTARD10STARD7POLBLMNA | |
| SCHEMBL1235844 | 0.79 | PCTP (1.00) | PCTPSTARD10STARD7LMNA | |
| SCHEMBL1235205 | 0.78 | PCTP (1.00) | PCTPSTARD10STARD7MEN1GAA | |
| SCHEMBL1235186 | 0.78 | PCTP (1.00) | PCTPSTARD10STARD7GAALMNA | |
| SCHEMBL1828300 | 0.77 | PDE4A (0.74) | PCTPSTARD10GAAKMT2APOLB | |
| SCHEMBL1233511 | 0.77 | PCTP (1.00) | PCTPSTARD10STARD7GAAPOLB | |
| SCHEMBL13275764 | 0.76 | PCTP (0.77) | PCTPSTARD10STARD7MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190201420-A1 | METHODS OF PREVENTION OR TREATMENT FOR PATHOLOGIC THROMBOSIS OR INFLAMMATION | THOMAS JEFFERSON UNIVERSITY (US) | 2019-07-04 | — | — | US | claimed |
| US-20160271150-A1 | METHODS OF PREVENTION OR TREATMENT FOR PATHOLOGIC THROMBOSIS OR INFLAMMATION | THOMAS JEFFERSON UNIVERSITY (US) | 2016-09-22 | — | — | US | claimed |
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | claimed |
| WO-2015065876-A1 | METHODS OF PREVENTION OR TREATMENT FOR PATHOLOGIC THROMBOSIS OR INFLAMMATION | THOMAS JEFFERSON UNIVERSITY (US) | 2015-05-07 | — | — | WO | claimed |
| US-20120264756-A1 | Phosphatidylcholine Transfer Protein Inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-10-18 | — | — | US | claimed |
| EP-2467362-A2 | PHOSPHATIDYLCHOLINE TRANSFER PROTEIN INHIBITORS | The Brigham and Women's Hospital, Inc. (US) | 2012-06-27 | — | — | EP | claimed |
| WO-2011022393-A2 | PHOSPHATIDYLCHOLINE TRANSFER PROTEIN INHIBITORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-02-24 | — | — | WO | claimed |
| US-20190201420-A1 | METHODS OF PREVENTION OR TREATMENT FOR PATHOLOGIC THROMBOSIS OR INFLAMMATION | THOMAS JEFFERSON UNIVERSITY (US) | 2019-07-04 | — | — | US | disclosed |
| US-9750757-B2 | Methods of prevention or treatment for pathologic thrombosis or inflammation | THOMAS JEFFERSON UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| US-9556129-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-9556129-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-9556129-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20160271150-A1 | METHODS OF PREVENTION OR TREATMENT FOR PATHOLOGIC THROMBOSIS OR INFLAMMATION | THOMAS JEFFERSON UNIVERSITY (US) | 2016-09-22 | — | — | US | disclosed |
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| WO-2015065876-A1 | METHODS OF PREVENTION OR TREATMENT FOR PATHOLOGIC THROMBOSIS OR INFLAMMATION | THOMAS JEFFERSON UNIVERSITY (US) | 2015-05-07 | — | — | WO | disclosed |
| US-20120264756-A1 | Phosphatidylcholine Transfer Protein Inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-20120264756-A1 | Phosphatidylcholine Transfer Protein Inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-20120264756-A1 | Phosphatidylcholine Transfer Protein Inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264756-A1 | Phosphatidylcholine Transfer Protein Inhibitors | PCTP, LCAT, CETP | PCTP 1/4885STARD10 1028/4885STARD7 117/4885 |
| US-20190201420-A1 | METHODS OF PREVENTION OR TREATMENT FOR PATHOLOGIC THROMBOSIS OR INFLAMMATION | PLAT, F2RL3, PLG | PCTP 36/4885STARD10 2235/4885STARD7 1872/4885 |
| US-20160271150-A1 | METHODS OF PREVENTION OR TREATMENT FOR PATHOLOGIC THROMBOSIS OR INFLAMMATION | PLAT, F2RL3, PLG | PCTP 36/4885STARD10 2235/4885STARD7 1872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.