Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxprenolol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 11/20 | 0.97 |
| ▸ | ADRB1 known ✓ | P08588 | 11/20 | 0.97 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.97 |
| ▸ | LMNA | P02545 | 4/20 | 0.97 |
| ▸ | HTR1A | P08908 | 4/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.97 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.97 |
| ▸ | HTR2A | P28223 | 4/20 | 0.97 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.97 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.97 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.70 |
| ▸ | HTR2B | P41595 | 3/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.70 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxprenolol SCHEMBL16311 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6LMNAHTR1A | |
| Oxprenolol SCHEMBL30209192 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6LMNAHTR1A | |
| Oxprenolol SCHEMBL17464297 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6LMNAHTR1A | |
| Oxprenolol SCHEMBL16310 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6LMNAHTR1A | |
| Oxprenolol SCHEMBL29698462 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6LMNAHTR1A | |
| Oxprenolol SCHEMBL29698472 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6LMNAHTR1A | |
| Oxprenolol SCHEMBL6508035 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6LMNAHTR1A | |
| Oxprenolol SCHEMBL29935146 | 0.97 | ADRB2 (0.97) | ADRB2ADRB1CYP2D6LMNAHTR1A | |
| Oxprenolol SCHEMBL628369 | 0.96 | ADRB2 (0.95) | ADRB2ADRB1CYP2D6LMNAHTR1A | |
| Oxprenolol SCHEMBL9697581 | 0.89 | ADRB2 (0.77) | ADRB2ADRB1CYP2D6LMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2963 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260145675-A1 | Functional Safety in Longitudinal Control Systems | BAYERISCHE MOTOREN WERKE AKTIENGESELLSCHAFT (DE) | 2026-05-28 | — | — | US | claimed |
| CN-114974360-B | Memory device | SK Hynix Inc. (KR) | 2026-05-26 | — | — | CN | claimed |
| CN-115427266-B | Separation device for a motor vehicle and energy supply network | BAYERISCHE MOTOREN WERKE AG (DE) | 2026-05-26 | — | — | CN | claimed |
| CN-122090906-A | Semiconductor memory device and method of operating the same | — | 2026-05-26 | — | — | CN | claimed |
| US-20260142525-A1 | Systems and Methods For Gearbox and Geardrive Assemblies | REGAL BELOIT AMERICA INC (US) | 2026-05-21 | — | — | US | claimed |
| EP-4262187-B1 | SENSOR DRIVING DEVICE | LG INNOTEK CO LTD (KR) | 2026-05-20 | — | — | EP | claimed |
| US-12632335-B2 | Data storage system with adaptive flash media scan | SK Hynix Inc. (KR) | 2026-05-19 | — | — | US | claimed |
| CN-122027748-A | Cross-border data dynamic management and control method and system based on flow analysis | 中国移动通信集团广西有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20260106448-A1 | RADIO ACCESSORY FAIL-SAFE CIRCUIT USING PASSIVE COMPONENTS | MOTOROLA SOLUTIONS INC (US) | 2026-04-16 | — | — | US | claimed |
| EP-4718262-A2 | WORKGROUP HIERARCHICAL CORE STRUCTURES FOR BUILDING REALTIME WORKGROUP SYSTEMS | HT Research Inc. (US) | 2026-04-01 | — | — | EP | claimed |
| WO-1998018610-A1 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | LENGERICH BERNHARD H VAN (US) | 1998-05-07 | — | — | WO | claimed |
| US-5700410-A | Method of manufacturing wax matrices | NIPPON SHINYAKU CO., LTD. (JP) | 1997-12-23 | — | — | US | claimed |
| EP-0580860-B1 | METHOD OF MANUFACTURING SOLID DISPERSION | NIPPON SHINYAKU CO LTD (JP) | 1997-10-22 | — | — | EP | claimed |
| US-5484776-A | REACTION WITH POLYSACCHARIDE | SYNEPOS AKTIENGESELLSCHAFT (LI) | 1996-01-16 | — | — | US | claimed |
| US-5288503-A | WATER-PERMEABLE DIFFUSION BARRIER OF POLYVINYL ALCOHOL | SRCHEM INCORPORATED (US) | 1994-02-22 | — | — | US | claimed |
| US-5260066-A | Cryogel bandage containing therapeutic agent | SRCHEM INCORPORATED (US) | 1993-11-09 | — | — | US | claimed |
| US-4952402-A | EDIBLE TASTE-MASKED DRUGS; MICROMATRIX ACTIVE MATERIAL COATED WITH NONTOXIC POLYMER; LIQUIDS; TABLETS | ELAN CORPORATION, P.L.C. (IE) | 1990-08-28 | — | — | US | claimed |
| EP-0189861-A2 | Percutaneous absorption accelerator for ionic water-soluble medicine | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | claimed |
| US-4369172-A | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose | FOREST LABORATORIES INC. (US) | 1983-01-18 | — | — | US | claimed |
| US-4139633-A | ISOPROPYLAMINOPROPANE DERIVATIVES, SUBSTITUTED BENZENE SULPHONAMIDE | CIBA-GEIGY CORPORATION (US) | 1979-02-13 | — | — | US | claimed |