Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL7640467 | 0.97 | POLB (0.32) | POLB | |
| Hydrochloric Acid SCHEMBL455000 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL675642 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL675299 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL676212 | 0.83 | — | — | |
| Fluoride Ion SCHEMBL7635122 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6448965 | 0.81 | — | — | |
| Fluoride Ion SCHEMBL7640497 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL6471847 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL7937640 | 0.79 | GPR3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080281063-A9 | Ethylene polymers and copolymers with high optical opacity and methods of making the same | SUKHADIA ASHISH M | 2008-11-13 | — | — | US | claimed |
| US-7323524-B2 | Tandem tetramerisation-polymerisation of olefins | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2008-01-29 | — | — | US | claimed |
| US-20060128910-A1 | Tandem tetramerisation-polymerisation of olefins | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2006-06-15 | — | — | US | claimed |
| CN-1738678-A | Alkene tandem type tetramer-polymerization method | SASOL TECH PTY LTD (ZA) | 2006-02-22 | — | — | CN | claimed |
| EP-1581343-A1 | TANDEM TETRAMERISATION-POLYMERISATION OF OLEFINS | Sasol Technology (PTY) Limited (ZA) | 2005-10-05 | — | — | EP | claimed |
| US-20050203261-A1 | Ethylene polymers and copolymers with high optical opacity and methods of making the same | CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. | 2005-09-15 | — | — | US | claimed |
| WO-2004056480-A1 | TANDEM TETRAMERISATION-POLYMERISATION OF OLEFINS | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2004-07-08 | — | — | WO | claimed |
| EP-0399347-B1 | Process for preparing a Syndio-isoblockpolymer | HOECHST AG (DE) | 1996-08-14 | — | — | EP | claimed |
| US-10421921-B2 | Lubricants from mixed alpha-olefin feeds | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2019-09-24 | — | — | US | disclosed |
| US-9796799-B2 | Transition metal compound, olefin polymerization catalyst, and olefin polymer production process | MITSUI CHEMICALS, INC. (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20170137737-A1 | Lubricants from Mixed Alpha-Olefin Feeds | EXXONMOBIL CHEMICAL PATENTS INC. | 2017-05-18 | — | — | US | disclosed |
| US-9593288-B2 | Lubricants from mixed alpha-olefin feeds | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-9540459-B2 | Production method of olefin polymer and olefin polymerization catalyst | MITSUI CHEMICALS, INC. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-9458261-B2 | Transition metal compound, olefin polymerization catalyst, and olefin polymer production process | MITSUI CHEMICALS, INC. (JP) | 2016-10-04 | — | — | US | disclosed |
| US-5883275-A | Process for the hydrogenation of metallocenes | TARGOR GMBH (DE) | 1999-03-16 | — | — | US | disclosed |
| US-5670681-A | Process for preparing a carbon-bridged biscyclopentadiene compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0786466-A1 | Transition metal compound, olefin polymerization catalyst comprising the compound, and process for production of olefin polymer | Tosoh Corporation (JP) | 1997-07-30 | — | — | EP | disclosed |
| US-5596052-A | CATALYTIC POLYMERIZATION OF PROPYLENE IN THE PRESENCE OF TITANIUM, ZIRCONIUM OR HAFNIUM COMPLEXES | MONTELL TECHNOLOGY COMPANY BV (NL) | 1997-01-21 | — | — | US | disclosed |
| EP-0693506-A2 | Process for the preparation of amorphous polymers of propylene | SPHERILENE S.p.A. (IT) | 1996-01-24 | — | — | EP | disclosed |
| EP-0604917-A2 | Atactic polypropylene | Montell Technology Company bv (NL) | 1994-07-06 | — | — | EP | disclosed |