Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MTOR | P42345 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2246169 | 1.00 | TRPV1 (0.76) | TRPV1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL13675903 | 0.86 | TRPV1 (1.00) | TRPV1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL16692728 | 0.86 | KDM4E (0.72) | TRPV1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL18010056 | 0.86 | KDM4E (0.72) | TRPV1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL14566157 | 0.85 | TRPV1 (0.79) | TRPV1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL13675900 | 0.84 | TRPV1 (1.00) | TRPV1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL13675902 | 0.84 | TRPV1 (1.00) | TRPV1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL13675796 | 0.84 | TRPV1 (0.77) | TRPV1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL13675907 | 0.84 | TRPV1 (1.00) | TRPV1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL13675914 | 0.84 | TRPV1 (0.77) | TRPV1MAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994167-B2 | Pentafluorosulphanyl-substituted compound and its use for producing medicaments | GRUENENTHAL GMBH (DE) | 2011-08-09 | — | — | US | disclosed |
| US-20090137594-A1 | Pentafluorosulphanyl-Substituted Compound And Its Use For Producing Medicaments | GRUENENTHAL GMGH (DE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137594-A1 | Pentafluorosulphanyl-Substituted Compound And Its Use For Producing Medicaments | FIBP, PFAS, FPR3 | TRPV1 445/4885MAPT 3864/4885MEN1 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.