Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.95 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466751 | 0.97 | — | — | |
| SCHEMBL5470583 | 0.97 | — | — | |
| SCHEMBL15760 | 0.97 | — | — | |
| SCHEMBL150736 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| Hydrochloric Acid SCHEMBL5166853 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| SCHEMBL892491 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| SCHEMBL7185714 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| SCHEMBL3291107 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| Methane SCHEMBL21143001 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| SCHEMBL1461668 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658188-B2 | Radio-opaque bioactive glass materials | Zurich, Eth (CH) | 2014-02-25 | — | — | US | disclosed |
| EP-2467119-A1 | RADIO-OPAQUE BIOACTIVE GLASS MATERIALS | ETH Zurich (CH) | 2012-06-27 | — | — | EP | disclosed |
| US-20120148646-A1 | RADIO-OPAQUE BIOACTIVE GLASS MATERIALS | UNIVERSITAT ZURICH (CH) | 2012-06-14 | — | — | US | disclosed |
| WO-2011020204-A1 | RADIO-OPAQUE BIOACTIVE GLASS MATERIALS | ETH Zürich (CH) | 2011-02-24 | — | — | WO | disclosed |