Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.95 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15760 | 0.97 | — | — | |
| SCHEMBL5470583 | 0.97 | — | — | |
| SCHEMBL9466751 | 0.97 | — | — | |
| SCHEMBL1235699 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| SCHEMBL3291107 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| SCHEMBL150736 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| SCHEMBL7185714 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| SCHEMBL362090 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| Methane SCHEMBL21143001 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 | |
| SCHEMBL892491 | 0.95 | TSHR (0.95) | TSHRSMN1; SMN2ALDH1A1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9587060-B2 | Functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2017-03-07 | — | — | US | disclosed |
| EP-2475615-A1 | CONTINUOUS SYNTHESIS OF CARBON-COATED LITHIUM-IRON-PHOSPHATE | Clariant International Ltd. (CH) | 2012-07-18 | — | — | EP | disclosed |
| US-20120168686-A1 | Continuous Synthesis of Carbon-Coated Lithium-Iron-Phosphate | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-07-05 | — | — | US | disclosed |
| WO-2011026581-A1 | CONTINUOUS SYNTHESIS OF CARBON-COATED LITHIUM-IRON-PHOSPHATE | CLARIANT INTERNATIONAL LTD (CH) | 2011-03-10 | — | — | WO | disclosed |
| US-7714089-B2 | Functionalized monomers and functionalized rubbery polymers made therewith | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2010-05-11 | — | — | US | disclosed |
| US-20090156769-A1 | FUNCTIONALIZED MONOMERS AND FUNCTIONALIZED RUBBERY POLYMERS MADE THEREWITH | THE GOODYEAR TIRE & RUBBER COMPANY | 2009-06-18 | — | — | US | disclosed |
| EP-1967531-A1 | Method of making alkoxy functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-09-10 | — | — | EP | disclosed |
| US-7335706-B1 | Method of making alkoxy functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-02-26 | — | — | US | disclosed |
| US-7304113-B2 | Method for partially and selectively hydrogenating polymers made of conjugated dienes | KRATON POLYMERS U.S. LLC (US) | 2007-12-04 | — | — | US | disclosed |
| US-7291687-B1 | Catalyst system for synthesizing rubbery polymers having a high trans microstructure content | THE GOODYEAR TIRE AND RUBBER COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| US-6995224-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-02-07 | — | — | US | disclosed |
| US-6936669-B2 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-08-30 | — | — | US | disclosed |
| US-6933358-B2 | Reacting secordary amine with 2,3-dihalopropene forming monomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-08-23 | — | — | US | disclosed |
| US-20050131181-A1 | FUNCTIONALIZED MONOMERS FOR SYNTHESIS OF RUBBERY POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY | 2005-06-16 | — | — | US | disclosed |
| WO-2005012366-A1 | METHOD FOR PARTIALLY AND SELECTIVELY HYDROGENATING POLYMERS MADE OF CONJUGATED DIENES | KRATON POLYMERS RESEARCH B.V. (NL) | 2005-02-10 | — | — | WO | disclosed |
| EP-1505080-A1 | Method for partially and selectively hydrogenating polymers made of conjugated dienes | KRATON Polymers Research B.V. (NL) | 2005-02-09 | — | — | EP | disclosed |
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-20040122194-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-20040048972-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-11 | — | — | US | disclosed |
| US-20040044157-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | PRMT1, DDR2, DNMT3A | TSHR 2194/4885SMN1; SMN2 2459/4885ALDH1A1 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.