SCHEMBL150736

SCHEMBL150736

CCCCC(C=O)CC.[Nd]

nearest known ligand 0.95

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.95
SMN1; SMN2 Q16637 1/20 0.95
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 2/20 0.39
CA2 P00918 5/20 0.38
MAPK1 P28482 1/20 0.38
CTSK P43235 2/20 0.38
CA1 P00915 3/20 0.37
TDP1 Q9NUW8 1/20 0.36
DNM1 Q05193 1/20 0.35
FDPS P14324 1/20 0.34
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH4 P08319 1/20 0.34
ADH7 P40394 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9466751 0.97
SCHEMBL5470583 0.97
SCHEMBL15760 0.97
SCHEMBL7185714 0.95 TSHR (0.95) TSHRSMN1; SMN2ALDH1A1CYP3A4CA2
SCHEMBL1461668 0.95 TSHR (0.95) TSHRSMN1; SMN2ALDH1A1CYP3A4CA2
Hydrochloric Acid SCHEMBL5166853 0.95 TSHR (0.95) TSHRSMN1; SMN2ALDH1A1CYP3A4CA2
SCHEMBL1235699 0.95 TSHR (0.95) TSHRSMN1; SMN2ALDH1A1CYP3A4CA2
SCHEMBL892491 0.95 TSHR (0.95) TSHRSMN1; SMN2ALDH1A1CYP3A4CA2
Methane SCHEMBL21143001 0.95 TSHR (0.95) TSHRSMN1; SMN2ALDH1A1CYP3A4CA2
SCHEMBL362090 0.95 TSHR (0.95) TSHRSMN1; SMN2ALDH1A1CYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113906058-B Modified high cis polybutadiene polymers, related methods and rubber compositions 普利司通美国轮胎运营有限责任公司 2024-05-17 CN disclosed
EP-3938412-B1 MODIFIED HIGH CIS POLYDIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE CORP (JP) 2024-04-24 EP disclosed
EP-3507104-B1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BYIN-SITU BRIDGESTONE CORP (JP) 2024-03-27 EP disclosed
EP-3538575-B1 HIGH CIS-1,4 BLOCK COPOLYMERS OF POLYBUTADIENE AND POLYISOPRENE BRIDGESTONE CORP (JP) 2024-03-13 EP disclosed
US-11884767-B2 High cis-1,4 block copolymers of polybutadiene and polyisoprene BRIDGESTONE CORPORATION (JP) 2024-01-30 US disclosed
CN-112029023-B Aged lanthanide-based catalyst systems and their use in the preparation of cis-1, 4-polydienes 株式会社普利司通 2023-10-20 CN disclosed
US-11767388-B1 Silicon-functionalized rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2023-09-26 US disclosed
WO-2023129959-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2023-07-06 WO disclosed
US-20230183399-A1 AGED LANTHANIDE-BASED CATALYST SYSTEMS AND THEIR USE IN THE PREPARATION OF CIS-1,4-POLYDIENES BRIDGESTONE CORPORATION (JP) 2023-06-15 US disclosed
US-20230144912-A1 METAL-BASED CATALYST FOR PRODUCING POLYDIENES BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2023-05-11 US disclosed
US-7008899-B2 Lanthanide-based catalyst composition for producing cis-1,4-polydienes BRIDGESTONE CORPORATION (JP) 2006-03-07 US disclosed
WO-2005061563-A1 BULK POLYMERIZATION PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2005-07-07 WO disclosed
US-20050131174-A1 Bulk polymerization process for producing polydienes BRIDGESTONE CORP. 2005-06-16 US disclosed
US-6897270-B2 Continuous process for the production of conjugated diene polymers having narrow molecular weight distribution and products therefrom BRIDGESTONE CORPORATION (JP) 2005-05-24 US disclosed
US-20050038215-A1 Lanthanide-based catalyst composition for producing cis-1,4-polydienes BRIDGESTONE CORPORATION (JP) 2005-02-17 US disclosed
US-20040116638-A1 Continuous process for the production of conjugated diene polymers having narrow molecular weight distribution and products therefrom BRIDGESTONE CORPORATION (JP) 2004-06-17 US disclosed
US-6699813-B2 COMPOSITION THAT IS COMBINATION OF OR REACTION PRODUCT OF LANTHANIDE COMPOUND, ALKYLATING AGENT, NICKEL-CONTAINING COMPOUND, AND OPTIONALLY HALOGEN-CONTAINING COMPOUND THAT INCLUDES ONE OR MORE LABILE HALOGEN ATOMS BRIDGESTONE CORPORATION (JP) 2004-03-02 US disclosed
EP-1370593-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF CONJUGATED DIENE POLYMERS HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION AND PRODUCTS THEREFROM Bridgestone Corporation (JP) 2003-12-17 EP disclosed
US-20030176276-A1 Lanthanide-based catalyst composition for the manufacture of polydienes BRIDGESTONE CORPORATION (JP) 2003-09-18 US disclosed
WO-2002068484-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF CONJUGATED DIENE POLYMERS HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION AND PRODUCTS THEREFROM BRIDGESTONE CORPORATION (JP) 2002-09-06 WO disclosed