Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12221886 | 0.91 | KDM4E (0.40) | L3MBTL1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13865066 | 0.91 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13241769 | 0.91 | BACE1 (0.40) | L3MBTL1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10036460 | 0.90 | BACE1 (0.46) | L3MBTL1ALDH1A1LMNATDP1MAPT | |
| SCHEMBL16394993 | 0.89 | MAPT (0.42) | L3MBTL1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11617807 | 0.88 | ALDH1A1 (0.49) | L3MBTL1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12220669 | 0.88 | ALDH1A1 (0.49) | L3MBTL1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14682220 | 0.86 | BACE1 (0.49) | L3MBTL1KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL10036456 | 0.86 | MAPT (0.39) | L3MBTL1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12289150 | 0.85 | CNR1 (0.43) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8007970-B2 | Low friction electrostatographic imaging member | XEROX CORPORATION (US) | 2011-08-30 | — | — | US | disclosed |
| US-20090253062-A1 | LOW FRICTION ELECTROSTATOGRAPHIC IMAGING MEMBER | XEROX CORPORATION (US) | 2009-10-08 | — | — | US | disclosed |