Benzocaine

Benzocaine

SCHEMBL1235972

CCOC(=O)c1ccc(N)cc1.CCOC(=O)c1ccc(N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
CYP1A2 P05177 3/20 1.00
CYP3A4 P08684 3/20 1.00
MAOA P21397 2/20 1.00
CA1 P00915 3/20 0.68
CA2 P00918 3/20 0.68
CA12 O43570 2/20 0.68
CA7 P43166 2/20 0.68
CA9 Q16790 2/20 0.68
CA14 Q9ULX7 2/20 0.68
ESR1 P03372 1/20 0.68
ESR2 Q92731 1/20 0.68
TSHR P16473 2/20 0.68
CYP2C9 P11712 1/20 0.68
CYP2C19 P33261 1/20 0.68
PDE4D Q08499 1/20 0.68
NPC1 O15118 2/20 0.64
RAB9A P51151 2/20 0.64
ALDH1A1 P00352 2/20 0.64
MAPT P10636 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzocaine SCHEMBL25100 1.00 LMNA (1.00) LMNACYP1A2CYP3A4MAOACA1
Benzocaine SCHEMBL11021778 0.98 LMNA (0.96) LMNACYP1A2CYP3A4MAOACA1
Benzocaine SCHEMBL944986 0.98 LMNA (0.96) LMNACYP1A2CYP3A4MAOACA1
Benzocaine SCHEMBL27914401 0.98 LMNA (0.96) LMNACYP1A2CYP3A4MAOACA1
Benzocaine SCHEMBL19031788 0.98 LMNA (0.96) LMNACYP1A2CYP3A4MAOACA1
Benzocaine SCHEMBL15200678 0.98 LMNA (0.96) LMNACYP1A2CYP3A4MAOACA1
Benzocaine SCHEMBL29029466 0.96 LMNA (0.92) LMNACYP1A2CYP3A4MAOACA1
Benzocaine SCHEMBL2389408 0.96 LMNA (0.92) LMNACYP1A2CYP3A4MAOACA1
SCHEMBL6323309 0.94 LMNA (0.89) LMNACYP1A2CYP3A4MAOACA1
SCHEMBL11374568 0.94 LMNA (0.89) LMNACYP1A2CYP3A4MAOACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111675805-B Toughened hard thermoplastic polyurethane elastomer and preparation method thereof 万华化学集团股份有限公司 2022-07-12 CN disclosed
EP-2467465-A1 ALCOHOLIC COMPOSITIONS HAVING A LOWERED RISK OF ACETALDEHYDEMIA Protia LLC (US) 2012-06-27 EP disclosed
WO-2011022682-A1 ALCOHOLIC COMPOSITIONS HAVING A LOWERED RISK OF ACETALDEHYDEMIA PROTIA LLC (US) 2011-02-24 WO disclosed
EP-0008976-A1 Digital F.S.K. modulator Etablissement Public de Diffusion dit "Télédiffusion de France" (FR) 1980-03-19 EP disclosed