Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1236339

CCCCC1C=C(C(C)(C)C)C=C1[Zr+2](=C(c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1)C1c2ccccc2-c2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOD2 Q9HC29 3/20 0.34
NOD1 Q9Y239 3/20 0.34
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
TP53BP1 Q12888 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1235713 0.95 TAS1R3 (0.34) NOD2NOD1HDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL1236875 0.92 HDAC3 (0.34) NOD2NOD1HDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL1236410 0.91 HDAC3 (0.33) NOD2NOD1HDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL1236180 0.91 MEN1 (0.33) NOD2NOD1HDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL1237140 0.91 HDAC3 (0.33) NOD2NOD1HDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL1235784 0.90 HDAC3 (0.34) NOD2NOD1HDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL1236435 0.90 CYP1A2 (0.33) NOD2NOD1ALDH1A1
Hydrochloric Acid SCHEMBL1236325 0.90 HDAC3 (0.32) NOD2NOD1HDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL1237014 0.90 HDAC3 (0.33) NOD2NOD1HDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL1237176 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1860149-B1 PROPYLENE POLYMER COMPOSITION, USE THEREOF, AND PROCESS FOR PRODUCTION OF THERMOPLASTIC POLYMER COMPOSITION MITSUI CHEMICALS INC (JP) 2016-06-15 EP disclosed
US-8802779-B2 Propylene-based polymer composition, use thereof, and method for producing thermoplastic polymer composition MITSUI CHEMICALS, INC. (JP) 2014-08-12 US disclosed
US-7879960-B2 methyl)(phenyl)methylene(3-tert-butyl-5-ethylcyclopentadienyl)(3,6-di-tert-butylfluorenyl)zirconium dichloride a metallocene], methylalumoxane, triisobutylaluminum containing catalyst system for propylene homo or copolymerization MITSUI CHEMICALS, INC. (JP) 2011-02-01 US disclosed
US-20080097055-A1 Process for Producing Propylene Polymer MITSUI CHEMICALS, INC. (JP) 2008-04-24 US disclosed
US-20080085977-A1 Propylene-based polymer composition, use thereof, and method for producing thermpolastic polymer composition MITSUI CHEMICALS, INC. 2008-04-10 US disclosed
EP-1860149-A1 PROPYLENE POLYMER COMPOSITION, USE THEREOF, AND PROCESS FOR PRODUCTION OF THERMOPLASTIC POLYMER COMPOSITION Mitsui Chemicals, Inc. (JP) 2007-11-28 EP disclosed
EP-1803742-A1 PROCESS FOR PRODUCING PROPYLENE POLYMER Mitsui Chemicals, Inc. (JP) 2007-07-04 EP disclosed