Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.65 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.65 |
| ▸ | ESR1 | P03372 | 3/20 | 0.65 |
| ▸ | STS | P08842 | 2/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | SHBG | P04278 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.65 |
| ▸ | AR | P10275 | 1/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.65 |
| ▸ | SNCA | P37840 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Almestrone SCHEMBL8089798 | 1.00 | CYP19A1 (0.65) | CYP19A1HSD17B1ESR1STSESR2 | |
| Almestrone SCHEMBL1657631 | 1.00 | CYP19A1 (0.65) | CYP19A1HSD17B1ESR1STSESR2 | |
| Almestrone SCHEMBL5983577 | 1.00 | CYP19A1 (0.65) | CYP19A1HSD17B1ESR1STSESR2 | |
| Almestrone SCHEMBL13216952 | 1.00 | CYP19A1 (0.65) | CYP19A1HSD17B1ESR1STSESR2 | |
| Almestrone SCHEMBL12364585 | 1.00 | CYP19A1 (0.65) | CYP19A1HSD17B1ESR1STSESR2 | |
| Almestrone SCHEMBL2244882 | 0.97 | CYP19A1 (0.61) | CYP19A1HSD17B1ESR1STSESR2 | |
| SCHEMBL8376406 | 0.88 | CYP19A1 (0.65) | CYP19A1HSD17B1ESR1STSESR2 | |
| SCHEMBL10083670 | 0.88 | CYP19A1 (0.65) | CYP19A1HSD17B1ESR1STSESR2 | |
| SCHEMBL10083683 | 0.88 | CYP19A1 (0.65) | CYP19A1HSD17B1ESR1STSESR2 | |
| SCHEMBL6879791 | 0.88 | CYP19A1 (0.65) | CYP19A1HSD17B1ESR1STSESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195942-A1 | METHOD OF MAKING AND USING 7ALPHA, 11BETA-DIMETHYL-17BETA-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN | 2011-08-11 | — | — | US | disclosed |
| US-20090023695-A1 | METHOD OF MAKING AND USING 7alpha,11beta-DIMETHYL-17beta-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023695-A1 | METHOD OF MAKING AND USING 7alpha,11beta-DIMETHYL-17beta-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE | HSD17B11, HSD17B13, HSD3B1 | CYP19A1 8/4885HSD17B1 11/4885ESR1 38/4885 |
| US-20110195942-A1 | METHOD OF MAKING AND USING 7ALPHA, 11BETA-DIMETHYL-17BETA-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE | HSD17B11, HSD17B13, HSD3B1 | CYP19A1 8/4885HSD17B1 11/4885ESR1 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.