Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366104 | 0.90 | HDAC3 (0.55) | L3MBTL1HPGDGAAEPHX1NPC1 | |
| SCHEMBL13209218 | 0.80 | GAA (1.00) | L3MBTL1HPGDGAAKDM4EEPHX1 | |
| SCHEMBL11976711 | 0.80 | L3MBTL1 (0.77) | L3MBTL1HPGDGAAKDM4EEPHX1 | |
| SCHEMBL7201053 | 0.80 | L3MBTL1 (0.89) | L3MBTL1HPGDGAATRPV1NPC1 | |
| SCHEMBL11591975 | 0.80 | GAA (0.59) | L3MBTL1HPGDGAARAB9AEPHX2 | |
| SCHEMBL1041910 | 0.78 | L3MBTL1 (0.74) | L3MBTL1HPGDGAAKDM4EEPHX1 | |
| SCHEMBL10632311 | 0.78 | L3MBTL1 (0.74) | L3MBTL1HPGDGAAKDM4EEPHX1 | |
| SCHEMBL7598872 | 0.78 | L3MBTL1 (0.74) | L3MBTL1HPGDGAATRPV1NPC1 | |
| SCHEMBL15093821 | 0.77 | EPHX2 (0.86) | L3MBTL1HPGDGAAKDM4EEPHX1 | |
| SCHEMBL164622 | 0.77 | L3MBTL1 (0.72) | L3MBTL1HPGDGAAKDM4EEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |