Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019835 | 0.94 | TRPV1 (0.69) | L3MBTL1HPGDNPC1RAB9AGAA | |
| SCHEMBL893485 | 0.92 | TRPV1 (0.72) | L3MBTL1HPGDNPC1RAB9AGAA | |
| SCHEMBL2024980 | 0.92 | TRPV1 (0.72) | L3MBTL1HPGDNPC1RAB9AGAA | |
| SCHEMBL2021336 | 0.92 | TRPV1 (0.72) | L3MBTL1HPGDNPC1RAB9AGAA | |
| SCHEMBL2021996 | 0.92 | TRPV1 (0.72) | L3MBTL1HPGDNPC1RAB9AGAA | |
| SCHEMBL15861957 | 0.92 | TRPV1 (0.72) | L3MBTL1HPGDNPC1RAB9AGAA | |
| SCHEMBL15093821 | 0.88 | EPHX2 (0.86) | L3MBTL1HPGDNPC1RAB9AGAA | |
| Butylbenzyl SCHEMBL28335644 | 0.87 | HPGD (0.62) | L3MBTL1HPGDNPC1RAB9AGAA | |
| Phenethylcarbamic Acid SCHEMBL249525 | 0.87 | CA12 (0.68) | L3MBTL1HPGDNPC1RAB9APOLB | |
| SCHEMBL5932867 | 0.86 | L3MBTL1 (0.70) | L3MBTL1HPGDNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | claimed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | claimed |
| EP-2194044-A1 | QUINOLONE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-06-09 | — | — | EP | claimed |
| CN-1898234-A | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | INCYTE CORP (US) | 2007-01-17 | — | — | CN | claimed |
| EP-3527600-B1 | ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER | ASAHI CHEMICAL IND (JP) | 2025-07-09 | — | — | EP | disclosed |
| EP-4551566-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2025-05-14 | — | — | EP | disclosed |
| EP-4395763-A1 | METHODS AND COMPOSITIONS FOR AMELIORATING BIOMARKERS ASSOCIATED WITH CARDIOVASCULAR RISK USING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE | AXSOME THERAPEUTICS (US) | 2024-07-10 | — | — | EP | disclosed |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | THE SCRIPPS RESEARCH INSTITUTE | 2024-04-02 | — | — | US | disclosed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| WO-2023233024-A1 | DPP9 BINDING COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2023-12-07 | — | — | WO | disclosed |
| US-20230114799-A1 | ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-04-13 | — | — | US | disclosed |
| WO-2023034944-A1 | METHODS AND COMPOSITIONS FOR AMELIORATING BIOMARKERS ASSOCIATED WITH CARDIOVASCULAR RISK USING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE | AXSOME THERAPEUTICS (US) | 2023-03-09 | — | — | WO | disclosed |
| CN-1366460-A | Preventive or therapeutic drugs for fibrosis containing chymase inhibitors as active ingredient | SUNTORY LTD (JP) | 2002-08-28 | — | — | CN | disclosed |
| CN-1366459-A | Preventive and therapeutic agent for various diseases associated with eosinophilia comprising chymase inhibitor as active ingredient | SUNTORY LTD (JP) | 2002-08-28 | — | — | CN | disclosed |
| CN-1366461-A | Preventive or therapeutic drugs for dermatitises containing chymase inhibitors as active ingredient | SUNTORY LTD (JP) | 2002-08-28 | — | — | CN | disclosed |
| CN-1335778-A | Blood vessel lipid deposition inhibitor containing chymotrypsin inhibitor | SUNTORY LTD (JP) | 2002-02-13 | — | — | CN | disclosed |
| US-5134151-A | Platelet Activating Factor Antagonist | J. URIACH & CIA (ES) | 1992-07-28 | — | — | US | disclosed |
| EP-0385490-A1 | 2-picolylamine derivates | J. URIACH & CIA. S.A. (ES) | 1990-09-05 | — | — | EP | disclosed |
| US-4319018-A | IN ACID CATALYST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1982-03-09 | — | — | US | disclosed |
| US-4062862-A | MUSCLE RELAXANT | NIPPON CHEMIPHAR CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230114799-A1 | ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER | IDH3A, IDH2, IDH3B | L3MBTL1 4577/4885HPGD 909/4885NPC1 1514/4885 |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | L3MBTL1 2056/4885HPGD 43/4885NPC1 581/4885 |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | TTR, MAP1LC3B, SAAL1 | L3MBTL1 336/4885HPGD 3113/4885NPC1 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.