Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Caprolactam SCHEMBL9116365 | 0.67 | CRBN (0.89) | FKBP5CRBNKDM4EGAAALDH1A1 | |
| Caprolactam SCHEMBL4016783 | 0.67 | — | — | |
| Caprolactam SCHEMBL9168784 | 0.67 | CRBN (0.89) | FKBP5CRBNKDM4EGAAALDH1A1 | |
| SCHEMBL1236530 | 0.67 | FKBP5 (0.42) | FKBP5CRBNKDM4EGAAHSD17B10 | |
| Caprolactam SCHEMBL28301539 | 0.65 | CRBN (0.84) | FKBP5CRBNKDM4EGAAALDH1A1 | |
| Caprolactam SCHEMBL29031904 | 0.65 | CRBN (0.84) | FKBP5CRBNKDM4EGAAALDH1A1 | |
| Caprolactam SCHEMBL27801926 | 0.65 | CRBN (0.84) | FKBP5CRBNKDM4EGAAALDH1A1 | |
| SCHEMBL2779608 | 0.65 | — | — | |
| SCHEMBL11226674 | 0.63 | TSHR (0.42) | FKBP5CRBNKDM4EGAAPOLB | |
| SCHEMBL11226687 | 0.63 | TSHR (0.42) | FKBP5CRBNKDM4EGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9301950-B2 | Adamantane analogs | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-04-05 | — | — | US | claimed |
| US-20120270917-A1 | ADAMANTANE ANALOGS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-10-25 | — | — | US | claimed |
| WO-2011022191-A1 | ADAMANTANE ANALOGS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-02-24 | — | — | WO | claimed |
| US-9301950-B2 | Adamantane analogs | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-04-05 | — | — | US | disclosed |
| US-20120270917-A1 | ADAMANTANE ANALOGS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-10-25 | — | — | US | disclosed |
| WO-2011022191-A1 | ADAMANTANE ANALOGS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270917-A1 | ADAMANTANE ANALOGS | HAVCR2, ADORA2A, ADORA1 | FKBP5 3954/4885CRBN 4018/4885KDM4E 4619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.