Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12367245 | 0.90 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL19344403 | 0.87 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL21547340 | 0.86 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL12367248 | 0.86 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL10816128 | 0.84 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL9344957 | 0.84 | TSHR (0.59) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL17410249 | 0.84 | TSHR (0.59) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL17880835 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL92203 | 0.83 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL12390255 | 0.82 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989651-B2 | trimethoxysilylpropyl-carbamic acid oxiranylmethyl ester; reacting glycidol with gamma-isocyanatopropyltriethoxysilane in presence of dibutyltin laurate catalyst | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080221238-A1 | Epoxysilanes, processes for their manufacture and curable compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-09-11 | — | — | US | disclosed |