Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12367246 | 0.90 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL17880835 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL12367248 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL23710790 | 0.84 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL13971019 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL12390255 | 0.82 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL24027612 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL92146 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL12367247 | 0.81 | ALDH1A1 (0.38) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL12384882 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989651-B2 | trimethoxysilylpropyl-carbamic acid oxiranylmethyl ester; reacting glycidol with gamma-isocyanatopropyltriethoxysilane in presence of dibutyltin laurate catalyst | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080221238-A1 | Epoxysilanes, processes for their manufacture and curable compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-09-11 | — | — | US | disclosed |