SCHEMBL12367277

SCHEMBL12367277

C[SiH2]CCCNC(=O)OCC1CO1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
BCHE P06276 2/20 0.39
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
ACHE P22303 8/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29008700 0.84 ALDH1A1 (0.44) ALDH1A1BCHETP53CYP3A4ACHE
SCHEMBL12367280 0.83 BCHE (0.39) ALDH1A1BCHETP53CYP3A4ACHE
SCHEMBL24262401 0.83 ACHE (0.58) BCHEACHE
Butane SCHEMBL11136278 0.83 BCHE (0.49) ALDH1A1BCHEACHE
SCHEMBL2260832 0.81 ALDH1A1 (0.41) ALDH1A1BCHETP53CYP3A4ACHE
SCHEMBL23521494 0.79 ALDH1A1 (0.40) ALDH1A1BCHETP53CYP3A4ACHE
SCHEMBL12367274 0.79 ALDH1A1 (0.41) ALDH1A1BCHETP53CYP3A4ACHE
SCHEMBL8162280 0.79 ALDH1A1 (0.50) ALDH1A1BCHETP53CYP3A4
SCHEMBL2266228 0.78 BCHE (0.40) ALDH1A1BCHETP53CYP3A4ACHE
SCHEMBL9478699 0.78 ALDH1A1 (0.44) ALDH1A1BCHETP53CYP3A4ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989651-B2 trimethoxysilylpropyl-carbamic acid oxiranylmethyl ester; reacting glycidol with gamma-isocyanatopropyltriethoxysilane in presence of dibutyltin laurate catalyst MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-08-02 US disclosed
US-20080221238-A1 Epoxysilanes, processes for their manufacture and curable compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2008-09-11 US disclosed