Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27417834 | 0.94 | APP (0.58) | ALOX5PTGS1APPMAPTKMT2A | |
| SCHEMBL12368110 | 0.86 | APP (0.49) | ALOX5PTGS1APPMAPTKMT2A | |
| SCHEMBL9321549 | 0.84 | ALOX5 (0.58) | ALOX5PTGS1APPMAPTKMT2A | |
| SCHEMBL27414830 | 0.78 | APP (0.63) | ALOX5PTGS1APPMAPTKMT2A | |
| SCHEMBL27160316 | 0.78 | APP (0.63) | ALOX5PTGS1APPMAPTKMT2A | |
| SCHEMBL27160317 | 0.78 | APP (0.63) | ALOX5PTGS1APPMAPTKMT2A | |
| SCHEMBL27160318 | 0.78 | APP (0.63) | ALOX5PTGS1APPMAPTKMT2A | |
| SCHEMBL27417832 | 0.73 | APP (0.58) | ALOX5PTGS1APPMAPTKMT2A | |
| SCHEMBL23987190 | 0.73 | APP (0.63) | ALOX5PTGS1APPMAPTKMT2A | |
| SCHEMBL23987113 | 0.72 | ALOX5 (0.59) | ALOX5PTGS1APPMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999004-B2 | Alpha -tocopherol, hydro-Q9 chromene, coenzyme Q9, cycloartane, 1-Feruloyl glycerol; activates estrogen receptors; improving menopause symptoms | NATIONAL TAIWAN UNIVERSITY (TW) | 2011-08-16 | — | — | US | disclosed |
| US-20080193432-A1 | Compounds Having Estrogenic Activity | NATIONAL TAIWAN UNIVERSITY (TW) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080193432-A1 | Compounds Having Estrogenic Activity | ESRRA, ESRRG, ESR2 | ALOX5 664/4885PTGS1 235/4885APP 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.