Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PNLIP | P16233 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27160318 | 0.86 | APP (0.63) | APPPTPN1MAPTKMT2AMEN1 | |
| SCHEMBL27160316 | 0.86 | APP (0.63) | APPPTPN1MAPTKMT2AMEN1 | |
| SCHEMBL27160317 | 0.86 | APP (0.63) | APPPTPN1MAPTKMT2AMEN1 | |
| SCHEMBL27414830 | 0.86 | APP (0.63) | APPPTPN1MAPTKMT2AMEN1 | |
| SCHEMBL27417834 | 0.81 | APP (0.58) | APPPTPN1MAPTKMT2AMEN1 | |
| SCHEMBL29651335 | 0.81 | VKORC1 (0.54) | APPPTPN1MAPTKMT2AMEN1 | |
| SCHEMBL29884371 | 0.79 | APP (0.51) | APPPTPN1MAPTKMT2AMEN1 | |
| SCHEMBL10603080 | 0.78 | APP (0.62) | APPPTPN1MAPTKMT2AMEN1 | |
| SCHEMBL9321549 | 0.78 | ALOX5 (0.58) | APPPTPN1MAPTKMT2AMEN1 | |
| SCHEMBL27417852 | 0.76 | ALOX5 (0.62) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228454-A1 | RING CLOSURE OF BENZOQUINONES CONTAINING AN UNSATURATED SIDE CHAIN USING A BASE IN TWO-PHASE SYSTEM | DSM IP ASSETS B.V. (NL) | 2024-07-11 | — | — | US | disclosed |
| US-20240228454-A1 | RING CLOSURE OF BENZOQUINONES CONTAINING AN UNSATURATED SIDE CHAIN USING A BASE IN TWO-PHASE SYSTEM | DSM IP ASSETS B.V. (NL) | 2024-07-11 | — | — | US | disclosed |
| US-20240217941-A1 | RING CLOSURE OF BENZOQUINONES CONTAINING AN UNSATURATED SIDE CHAIN USING A BASIC CATALYST | DSM IP ASSETS B.V. (NL) | 2024-07-04 | — | — | US | disclosed |
| US-20240217941-A1 | RING CLOSURE OF BENZOQUINONES CONTAINING AN UNSATURATED SIDE CHAIN USING A BASIC CATALYST | DSM IP ASSETS B.V. (NL) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217941-A1 | RING CLOSURE OF BENZOQUINONES CONTAINING AN UNSATURATED SIDE CHAIN USING A BASIC CATALYST | SQLE, VKORC1, TTPA | APP 3682/4885PTPN1 4845/4885MAPT 4633/4885 |
| US-20240228454-A1 | RING CLOSURE OF BENZOQUINONES CONTAINING AN UNSATURATED SIDE CHAIN USING A BASE IN TWO-PHASE SYSTEM | TTPA, SQLE, VKORC1 | APP 3586/4885PTPN1 4874/4885MAPT 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.