Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15042298 | 0.91 | CYP11B1 (0.48) | CYP11B1KCNA5CYP19A1ALDH1A1KDM4E | |
| SCHEMBL12368348 | 0.89 | ALDH1A1 (0.35) | CYP11B1PTGDR2ALDH1A1MAPTKDM4E | |
| SCHEMBL18382439 | 0.86 | KCNA5 (0.41) | CYP11B1KCNA5CYP19A1PTGDR2KDM4E | |
| SCHEMBL12011512 | 0.85 | BACE1 (0.34) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL15042299 | 0.85 | BACE1 (0.34) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL15042283 | 0.84 | IMPDH2 (0.39) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL15042343 | 0.82 | IMPDH2 (0.33) | ALDH1A1NPC1MAPTKDM4ELMNA | |
| SCHEMBL12700367 | 0.80 | KDM4E (0.33) | PTGDR2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL18382339 | 0.79 | CYP11B1 (0.39) | CYP11B1KCNA5CYP19A1PTGDR2TNF | |
| SCHEMBL23085054 | 0.79 | CYP11B1 (0.39) | CYP11B1KCNA5PTGDR2TNFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8512878-B2 | Diaminopyrene derivative and organic EL device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2013-08-20 | — | — | US | disclosed |
| US-8512878-B2 | Diaminopyrene derivative and organic EL device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2013-08-20 | — | — | US | disclosed |
| US-20110193064-A1 | DIAMINOPYRENE DERIVATIVE AND ORGANIC EL DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-08-11 | — | — | US | disclosed |
| US-20110193064-A1 | DIAMINOPYRENE DERIVATIVE AND ORGANIC EL DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110193064-A1 | DIAMINOPYRENE DERIVATIVE AND ORGANIC EL DEVICE USING THE SAME | ELP1, EED, ESR1 | CYP11B1 3687/4885KCNA5 1615/4885CYP19A1 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.