SCHEMBL12370943

SCHEMBL12370943

O=C1CC(C2CCC(C3CCC(c4ccc(F)cc4)CC3)CC2)O1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAP1LC3B Q9GZQ8 1/20 0.38
MAOB P27338 5/20 0.37
TDP1 Q9NUW8 2/20 0.37
FADS1 O60427 2/20 0.34
ALPL P05186 1/20 0.34
GRM2 Q14416 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
AKR1A1 P14550 1/20 0.33
AKR1B1 P15121 1/20 0.33
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12370993 0.98 MAP1LC3B (0.39) MAP1LC3BMAOBTDP1FADS1ALPL
SCHEMBL12371032 0.90 NOTUM (0.38) NOTUM
SCHEMBL12371016 0.85 TNKS (0.37) MAOBTDP1NOTUM
SCHEMBL12370942 0.84 SLC2A1 (0.41) MAP1LC3B
SCHEMBL2273765 0.84 MAP1LC3B (0.39) MAP1LC3BMAOB
SCHEMBL2271030 0.84 MAP1LC3B (0.39) MAP1LC3BMAOB
SCHEMBL2271037 0.84 MAP1LC3B (0.39) MAP1LC3BMAOB
SCHEMBL2271032 0.84 MAP1LC3B (0.39) MAP1LC3BMAOB
SCHEMBL2273714 0.84 MAP1LC3B (0.39) MAP1LC3BMAOB
SCHEMBL12370948 0.83 USP5 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999123-B2 2-oxetanone derivative and process for production thereof JNC CORPORATION (JP) 2011-08-16 US disclosed
US-7999123-B2 2-oxetanone derivative and process for production thereof JNC CORPORATION (JP) 2011-08-16 US disclosed
US-20090275756-A1 2-OXETANONE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF CHISSO CORPORATION (JP) 2009-11-05 US disclosed
US-20090275756-A1 2-OXETANONE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF CHISSO CORPORATION (JP) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275756-A1 2-OXETANONE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF OGDH, OXGR1, OXER1 MAP1LC3B 3038/4885MAOB 184/4885TDP1 4596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.