Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | POLH | Q9Y253 | 3/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.52 |
| ▸ | BCL9 | O00512 | 3/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369818 | 0.89 | ACE2 (0.69) | ACE2ADORA3PTGS1BCL9CTNNB1 | |
| SCHEMBL13445534 | 0.89 | ACE2 (0.69) | ACE2ADORA3PTGS1BCL9CTNNB1 | |
| SCHEMBL13707581 | 0.87 | ACE2 (0.76) | ACE2ADORA3PTGS1POLHABCG2 | |
| SCHEMBL14370202 | 0.85 | ACE2 (0.64) | ACE2ADORA3PTGS1POLHABCG2 | |
| SCHEMBL14594144 | 0.84 | ACE2 (0.83) | ACE2ADORA3PTGS1POLHABCG2 | |
| SCHEMBL17656830 | 0.82 | ACE2 (0.68) | ACE2ADORA3PTGS1POLHABCG2 | |
| SCHEMBL15918780 | 0.82 | ACE2 (0.74) | ACE2POLHABCB1BCL9CTNNB1 | |
| SCHEMBL14254542 | 0.80 | ABCB1 (0.60) | ACE2ABCB1ABCC1XDH | |
| SCHEMBL17620271 | 0.79 | ACE2 (0.83) | ACE2ADORA3PTGS1POLHABCG2 | |
| SCHEMBL17620379 | 0.79 | ACE2 (0.94) | ACE2ADORA3PTGS1POLHABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003688-B2 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | IMMUPHARM APS (DK) | 2011-08-23 | — | — | US | disclosed |
| US-7671086-B2 | Pharmaceutical compositions comprising flavonoids and menthol | IMMUPHARM A/S (DK) | 2010-03-02 | — | — | US | disclosed |
| US-7585890-B2 | Pharmaceutical compositions comprising flavonoids and menthol | IMMUNPHARM A/S (DK) | 2009-09-08 | — | — | US | disclosed |
| US-7166640-B2 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | IMMUPHARM APS (DK) | 2007-01-23 | — | — | US | disclosed |