SCHEMBL12371896

SCHEMBL12371896

C=CCOc1nc2ccccc2s1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 6/20 0.54
PTGS2 P35354 6/20 0.54
L3MBTL1 Q9Y468 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.48
TP53 P04637 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
MAPK1 P28482 1/20 0.44
RAB9A P51151 1/20 0.44
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29882474 1.00 PTGS1 (0.54) PTGS1PTGS2L3MBTL1MEN1KMT2A
SCHEMBL29286221 0.81 PTGS1 (0.44) PTGS1PTGS2L3MBTL1MEN1KMT2A
SCHEMBL29881925 0.81 PTGS1 (0.55) PTGS1PTGS2L3MBTL1MEN1KMT2A
SCHEMBL11349174 0.81 PTGS1 (0.51) PTGS1PTGS2L3MBTL1MEN1KMT2A
SCHEMBL28820756 0.81 PTGS1 (0.55) PTGS1PTGS2L3MBTL1MEN1KMT2A
SCHEMBL19614387 0.80 PDE10A (0.40) PTGS1PTGS2L3MBTL1MEN1KMT2A
SCHEMBL72049 0.78 PTGS1 (0.61) PTGS1PTGS2L3MBTL1MEN1KMT2A
SCHEMBL6842459 0.77 PTGS1 (0.58) PTGS1PTGS2L3MBTL1MEN1KMT2A
SCHEMBL7352333 0.77 PTGS1 (0.62) PTGS1PTGS2L3MBTL1MEN1KMT2A
SCHEMBL1632866 0.77 PTGS1 (0.58) PTGS1PTGS2L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476874-B Two-part cyanoacrylate curable adhesive systems 汉高知识产权控股有限责任公司 2021-04-16 CN claimed
US-20240318052-A1 METHOD OF UNDERWATER BONDING HENKEL AG & CO KGAA (DE) 2024-09-26 US disclosed
CN-114907514-A Multifunctional fiber and preparation method and application thereof 北京洁尔爽高科技有限公司 2022-08-16 CN disclosed
CN-109476874-B Two-part cyanoacrylate curable adhesive systems 汉高知识产权控股有限责任公司 2021-04-16 CN disclosed
US-8933168-B2 Activators for two part cyanoacrylate adhesives Henkel IP & Holding GmbH (DE) 2015-01-13 US disclosed
US-8933168-B2 Activators for two part cyanoacrylate adhesives Henkel IP & Holding GmbH (DE) 2015-01-13 US disclosed
US-20110196092-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R&D) LIMITED (IE) 2011-08-11 US disclosed
US-20110196092-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R&D) LIMITED (IE) 2011-08-11 US disclosed
WO-2010046412-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R & D) LIMITED (IE) 2010-04-29 WO disclosed