Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158221 | 0.86 | PTGS1 (0.61) | PTGS1PTGS2KMT2AMEN1NPC1 | |
| SCHEMBL12110104 | 0.85 | PTGS1 (0.65) | PTGS1PTGS2KMT2AMEN1F2RL3 | |
| SCHEMBL9167195 | 0.84 | PTGS1 (0.64) | PTGS1PTGS2KMT2AMEN1NPC1 | |
| SCHEMBL28282484 | 0.83 | PTGS1 (0.58) | PTGS1PTGS2KMT2AMEN1NPC1 | |
| SCHEMBL30423366 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2KMT2AMEN1NPC1 | |
| SCHEMBL12371895 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2KMT2AMEN1NPC1 | |
| SCHEMBL30423741 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2KMT2AMEN1NPC1 | |
| SCHEMBL12371894 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2KMT2AMEN1NPC1 | |
| SCHEMBL7352333 | 0.81 | PTGS1 (0.62) | PTGS1PTGS2KMT2AMEN1NPC1 | |
| SCHEMBL1632866 | 0.81 | PTGS1 (0.58) | PTGS1PTGS2KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271650-B1 | Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands | BRISTOL MYERS SQUIBB CO (US) | 2015-09-16 | — | — | EP | claimed |
| EP-2493893-B1 | AZABICYCLO[2.2.1]HEPTANE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2014-01-15 | — | — | EP | claimed |
| US-4225705-A | QUATERNIZATION OF A BENZOTHIAZOLE, CONDENSED WITH A BENZOTHIAZOLIUM BETAINE | BADER HENRY | 1980-09-30 | — | — | US | claimed |
| CN-116730948-A | Method for synthesizing N-cyclohexyl-2-benzothiazole | 圣奥化学科技有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-10945996-B2 | Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2021-03-16 | — | — | US | disclosed |
| US-20190209531-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2019-07-11 | — | — | US | disclosed |
| CN-106632304-B | A kind of two-photon RNA fluorescence probe and its application in living cells imaging | 山东省科学院新材料研究所 | 2019-03-26 | — | — | CN | disclosed |
| US-20180000793-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | ABEL-SANTOS ERNESTO (US) | 2018-01-04 | — | — | US | disclosed |
| US-20170190923-A1 | NEAR-INFRARED ABSORPTION COMPOSITION, CURABLE COMPOSITION, CURED FILM, NEAR-INFRARED CUT FILTER, SOLID-STATE IMAGING DEVICE, INFRARED SENSOR, CAMERA MODULE, PROCESSED COLORING AGENT, AND METHOD OF MANUFACTURING PROCESSED COLORING AGENT | FUJIFILM CORPORATION (JP) | 2017-07-06 | — | — | US | disclosed |
| US-20170190923-A1 | NEAR-INFRARED ABSORPTION COMPOSITION, CURABLE COMPOSITION, CURED FILM, NEAR-INFRARED CUT FILTER, SOLID-STATE IMAGING DEVICE, INFRARED SENSOR, CAMERA MODULE, PROCESSED COLORING AGENT, AND METHOD OF MANUFACTURING PROCESSED COLORING AGENT | FUJIFILM CORPORATION (JP) | 2017-07-06 | — | — | US | disclosed |
| EP-2739612-B1 | COMPOUNDS AND COMPOSITIONS FOR USE IN AUGMENTATION OF GLUCOSE UPTAKE AND INSULIN SECRETION | YISSUM RES DEV CO (IL) | 2017-06-21 | — | — | EP | disclosed |
| EP-0985674-B1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS | MITSUBISHI CHEM CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6255515-B1 | COORDINATION POLYMERIZATION CATALYSTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0985674-A1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-15 | — | — | EP | disclosed |
| WO-1996035422-A1 | METHODS FOR INHIBITING BONE LOSS | ELI LILLY AND COMPANY (US) | 1996-11-14 | — | — | WO | disclosed |
| US-5166042-A | Multilayer color photographic member | FUJI PHOTO FILM CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0357082-A2 | Silver halide photographic emulsions | FUJI PHOTO FILM CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4225705-A | QUATERNIZATION OF A BENZOTHIAZOLE, CONDENSED WITH A BENZOTHIAZOLIUM BETAINE | BADER HENRY | 1980-09-30 | — | — | US | disclosed |
| US-4201707-A | Methine dyestuffs containing a phenyl azo group | BAYER AKTIENGESELLSCHAFT (DE) | 1980-05-06 | — | — | US | disclosed |
| US-4138570-A | METHINE DYE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10945996-B2 | Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis | CASP3, SI, PYCARD | PTGS1 521/4885PTGS2 638/4885KMT2A 4855/4885 |
| US-20190209531-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | CASP3, SI, PYCARD | PTGS1 521/4885PTGS2 638/4885KMT2A 4855/4885 |
| US-20180000793-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | CASP3, SI, PYCARD | PTGS1 521/4885PTGS2 638/4885KMT2A 4855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.