SCHEMBL29286221

SCHEMBL29286221

C=CCOc1nc2ccccc2s1.Cc1nc2c(F)c(F)c(F)c(F)c2s1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 6/20 0.44
PTGS2 P35354 6/20 0.44
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.34
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
PPARG P37231 3/20 0.34
PPARA Q07869 3/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TLR8 Q9NR97 1/20 0.33
TLR7 Q9NYK1 1/20 0.33
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12371896 0.81 PTGS1 (0.54) PTGS1PTGS2KMT2AMEN1L3MBTL1
SCHEMBL29882474 0.81 PTGS1 (0.54) PTGS1PTGS2KMT2AMEN1L3MBTL1
SCHEMBL19614387 0.73 PDE10A (0.40) PTGS1PTGS2KMT2AMEN1L3MBTL1
SCHEMBL11349174 0.68 PTGS1 (0.51) PTGS1PTGS2KMT2AMEN1L3MBTL1
SCHEMBL12371889 0.68 KDM4E (0.36) NPC1RAB9ATLR8TLR7KDM4E
SCHEMBL8050983 0.66 SETDB1 (0.43) KMT2AMEN1L3MBTL1MAPTALDH1A1
SCHEMBL7352333 0.65 PTGS1 (0.62) PTGS1PTGS2KMT2AMEN1L3MBTL1
SCHEMBL6842459 0.65 PTGS1 (0.58) PTGS1PTGS2KMT2AMEN1L3MBTL1
SCHEMBL29881925 0.65 PTGS1 (0.55) PTGS1PTGS2KMT2AMEN1L3MBTL1
SCHEMBL28820756 0.65 PTGS1 (0.55) PTGS1PTGS2KMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN claimed
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN disclosed