Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30341710 | 1.00 | FOLH1 (0.60) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL9169411 | 1.00 | FOLH1 (0.60) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL30983347 | 1.00 | FOLH1 (0.60) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL19514702 | 1.00 | FOLH1 (0.60) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL30918604 | 1.00 | FOLH1 (0.60) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL31003995 | 1.00 | FOLH1 (0.60) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL9175340 | 0.99 | FOLH1 (0.59) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL31004008 | 0.94 | FOLH1 (0.69) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL30302185 | 0.94 | FOLH1 (0.69) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL1009859 | 0.94 | FOLH1 (0.56) | FOLH1TDP1CASP3CASP1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020232440-A1 | PEPTIDE-BASED INHIBITORS THAT BLOCK AGGREGATION, SEEDING AND CROSS-SEEDING OF AMYLOID BETA AND TAU | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-11-19 | — | — | WO | disclosed |
| WO-2018170324-A1 | STRUCTURE-BASED PEPTIDE INHIBITORS THAT TARGET THE TAU VQIINK FIBRILLIZATION SEGMENT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-09-20 | — | — | WO | disclosed |
| US-7989600-B2 | Bioconjugation; drug screening | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. | 2011-08-02 | — | — | US | disclosed |
| US-20080241959-A1 | Macrolide Compounds Containing Biotin and Photo-Affinity Group for Macrolide Target Identification | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241959-A1 | Macrolide Compounds Containing Biotin and Photo-Affinity Group for Macrolide Target Identification | BTD, HLCS, MRPL12 | FOLH1 3502/4885TDP1 4699/4885CASP3 4637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.