Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13330400 | 1.00 | HPGD (0.65) | HPGDSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL12372653 | 1.00 | HPGD (0.65) | HPGDSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL12372662 | 0.99 | HPGD (0.64) | HPGDSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL12372657 | 0.92 | POLB (0.64) | HPGDSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL20682180 | 0.90 | POLB (0.62) | HPGDSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL12410680 | 0.84 | POLB (0.56) | HPGDSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL8864677 | 0.83 | HPGD (0.70) | HPGDSMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL15172051 | 0.83 | POLB (0.55) | HPGDSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL12341733 | 0.79 | KDM4E (0.53) | HPGDSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL758589 | 0.79 | KDM4E (0.53) | HPGDSMN1; SMN2ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110206880-A1 | HIGH TEMPERATURE MELT PROCESSABLE SEMI-CRYSTALLINE POLY(ARYL ETHER KETONE) CONTAINING A (4-HYDROXYPHENYL)PHTHALAZIN-1(2H)-ONE COMONOMER UNIT | WANG YI-FENG | 2011-08-25 | — | — | US | disclosed |
| US-20100113688-A1 | High temperature melt processable semi-crystalline poly (aryl ether ketone) containing a (4-hydroxyphenyl) phthalazin-1 (2H)-one comonomer unit | POLYMICS, LTD. | 2010-05-06 | — | — | US | disclosed |