Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20682180 | 0.99 | POLB (0.62) | POLBHPGDSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL12410680 | 0.92 | POLB (0.56) | POLBHPGDSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL12372653 | 0.92 | HPGD (0.65) | POLBHPGDSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL13330400 | 0.92 | HPGD (0.65) | POLBHPGDSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL12372655 | 0.92 | HPGD (0.65) | POLBHPGDSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL8864677 | 0.91 | HPGD (0.70) | POLBHPGDSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL12372662 | 0.91 | HPGD (0.64) | POLBHPGDSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL15172051 | 0.91 | POLB (0.55) | POLBHPGDSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL30719611 | 0.84 | KDM4E (0.72) | HPGDSMN1; SMN2MAPK1ALDH1A1HRH3 | |
| SCHEMBL8864708 | 0.84 | KDM4E (0.72) | HPGDSMN1; SMN2MAPK1ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110206880-A1 | HIGH TEMPERATURE MELT PROCESSABLE SEMI-CRYSTALLINE POLY(ARYL ETHER KETONE) CONTAINING A (4-HYDROXYPHENYL)PHTHALAZIN-1(2H)-ONE COMONOMER UNIT | WANG YI-FENG | 2011-08-25 | — | — | US | disclosed |