SCHEMBL758589

SCHEMBL758589

COc1ccc(C(=O)c2ccc(-n3nc(-c4ccc(C)cc4)c4ccccc4c3=O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
ALDH1A1 P00352 4/20 0.53
HPGD P15428 3/20 0.53
LMNA P02545 1/20 0.53
PDE4A P27815 1/20 0.52
PDE4B Q07343 1/20 0.52
PDE4C Q08493 1/20 0.52
PDE4D Q08499 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
HTT P42858 2/20 0.50
GAA P10253 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
NPSR1 Q6W5P4 3/20 0.49
RAB9A P51151 2/20 0.49
ALOX5 P09917 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
ADORA3 P0DMS8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12341733 1.00 KDM4E (0.53) KDM4EALDH1A1HPGDLMNAPDE4A
SCHEMBL17366542 0.91 ALOX5 (0.51) KDM4EALDH1A1HPGDLMNAPDE4A
SCHEMBL13400647 0.86 PDE4A (0.53) KDM4EALDH1A1HPGDLMNAPDE4A
SCHEMBL12341740 0.85 PDE4A (0.62) KDM4EALDH1A1HPGDLMNAPDE4A
SCHEMBL12341732 0.85 ALOX5 (0.60) KDM4EALDH1A1HPGDLMNAPDE4A
SCHEMBL18348589 0.79 ALOX5 (0.40) KDM4EALDH1A1HPGDLMNAPDE4A
SCHEMBL13444649 0.79 SMN1; SMN2 (0.51) KDM4EALDH1A1HPGDL3MBTL1GAA
SCHEMBL13330400 0.79 HPGD (0.65) KDM4EALDH1A1HPGDLMNAL3MBTL1
SCHEMBL12372655 0.79 HPGD (0.65) KDM4EALDH1A1HPGDLMNAL3MBTL1
SCHEMBL12372653 0.79 HPGD (0.65) KDM4EALDH1A1HPGDLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211558-B2 Crosslinked polymer electrolyte and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-03 US disclosed
US-8138231-B2 Polymer having oxycarbon group, and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-20 US disclosed
US-20090274943-A1 CROSSLINKED POLYMER ELECTROLYTE AND METHOD FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-11-05 US disclosed
US-20090233142-A2 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-17 US disclosed
US-20090110995-A1 POLYMER HAVING OXYCARBON GROUP, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed
US-20070218335-A1 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF KAO CORPORATION (JP) 2007-09-20 US disclosed