Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403338 | 0.82 | CA1 (0.47) | FAAHCYP2D6TRPM8 | |
| SCHEMBL8303438 | 0.79 | CYP2A6 (0.50) | CYP2A6FAAHL3MBTL1PRKCICDK4 | |
| SCHEMBL1255190 | 0.79 | CYP2A6 (0.46) | CYP2A6FAAHL3MBTL1PRKCI | |
| SCHEMBL25185804 | 0.78 | CYP2A6 (0.49) | CYP2A6FAAHL3MBTL1TRPM8PRKCI | |
| SCHEMBL14473327 | 0.78 | CYP2A6 (0.49) | CYP2A6FAAHL3MBTL1TRPM8PRKCI | |
| SCHEMBL111470 | 0.78 | CYP2A6 (0.49) | CYP2A6FAAHL3MBTL1PRKCI | |
| SCHEMBL6583538 | 0.78 | CYP2A6 (0.49) | CYP2A6FAAHL3MBTL1TRPM8PRKCI | |
| Hydrochloric Acid SCHEMBL27898641 | 0.76 | CYP2A6 (0.47) | CYP2A6FAAHL3MBTL1BRD4TRPM8 | |
| SCHEMBL17316721 | 0.76 | KDM4E (0.54) | CYP2A6FAAHLMNA | |
| SCHEMBL2176865 | 0.76 | ALOX5 (0.58) | SLC6A2SLC6A3LMNACDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455516-B2 | HIV-1 fusion inhibitors and methods | TOURO UNIVERSITY (US) | 2013-06-04 | — | — | US | disclosed |
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | TOURO UNIVERSITY (US) | 2011-08-04 | — | — | US | disclosed |
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | TOURO UNIVERSITY (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | FLI1, API5, MAVS | CYP2A6 4316/4885FAAH 1011/4885IDH1 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.