Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 4/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403338 | 0.83 | CA1 (0.47) | CA1CA2CA9FOLH1MEP1B | |
| SCHEMBL26119911 | 0.82 | MAPK11 (0.53) | ALDH1A1MAPK11MAPK14MCL1 | |
| SCHEMBL2273602 | 0.79 | PLG (0.49) | CA1CA2CA9FOLH1HTT | |
| SCHEMBL11977074 | 0.78 | PTGS2 (0.47) | CA2ALDH1A1MAPK11MAPK14HIF1A | |
| SCHEMBL2277153 | 0.78 | F2 (0.51) | CA1CA2CA9FOLH1MRGPRX4 | |
| SCHEMBL70351 | 0.75 | FOLH1 (0.70) | CA1CA2CA9FOLH1MEP1B | |
| SCHEMBL30791058 | 0.75 | FOLH1 (0.70) | CA1CA2CA9FOLH1MEP1B | |
| SCHEMBL758075 | 0.74 | MAPK11 (0.38) | CA2CA9MAPK11MAPK14 | |
| SCHEMBL2278773 | 0.74 | MRGPRX4 (0.52) | MEP1BMRGPRX4 | |
| SCHEMBL2277407 | 0.74 | HDAC8 (0.61) | MEP1BMRGPRX4BCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | TOURO UNIVERSITY (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | FLI1, API5, MAVS | CA1 4364/4885CA2 4377/4885CA9 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.