Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374338 | 0.92 | NPC1 (0.37) | PDK2MAPTKMT2ADRD2DRD4 | |
| SCHEMBL12374337 | 0.88 | PTGS2 (0.36) | PDK2NPC1RAB9AELANEMAPK1 | |
| SCHEMBL12374343 | 0.87 | PDK2 (0.43) | PDK2MAPTKMT2ADRD2DRD4 | |
| SCHEMBL12374332 | 0.86 | PDK2 (0.39) | PDK2MAPTKMT2AMEN1NPC1 | |
| SCHEMBL12620452 | 0.84 | PDK2 (0.45) | PDK2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL13589739 | 0.83 | NR5A1 (0.46) | PDK2NPC1RAB9ALTA4HPLK1 | |
| SCHEMBL6123912 | 0.83 | NR5A1 (0.46) | PDK2NPC1RAB9ALTA4HPLK1 | |
| SCHEMBL12619832 | 0.82 | LTA4H (0.46) | PDK2MAPTKMT2ADRD2DRD4 | |
| SCHEMBL12018767 | 0.82 | PDK2 (0.45) | PDK2NPC1RAB9ALTA4HPLK1 | |
| SCHEMBL12620447 | 0.81 | PDK2 (0.43) | PDK2MAPTKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110187266-A1 | POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-04 | — | — | US | disclosed |