SCHEMBL12374340

SCHEMBL12374340

COc1cccc(C2(c3cccc(OC)c3)c3cc(C)ccc3-c3ccc(C)cc32)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.52
KDM1A O60341 1/20 0.43
MAOB P27338 3/20 0.41
PDE4D Q08499 1/20 0.40
TP53 P04637 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
ALKBH3 Q96Q83 1/20 0.39
CHRNA1 P02708 1/20 0.38
CHRNG P07510 1/20 0.38
CHRNB1 P11230 1/20 0.38
CHRNB2 P17787 1/20 0.38
SLC6A2 P23975 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA4 P43681 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CHRND Q07001 1/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 2/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18722697 0.93 ACHE (0.49) ACHEKDM1AMAOBPDE4DTP53
SCHEMBL15854778 0.85 ALDH1A1 (0.39) ACHEMAOBPDE4DTP53SMN1; SMN2
SCHEMBL14191205 0.81 ESR1 (0.47) ACHEKDM1ASMN1; SMN2ALDH1A1CYP3A4
SCHEMBL12374341 0.81 ACHE (0.48) ACHEMAOBPDE4DTP53ALKBH3
SCHEMBL13828491 0.80 ACHE (0.52) ACHEPDE4DALKBH3ALDH1A1CA1
SCHEMBL14584274 0.79 ESR1 (0.45) ACHEKDM1AMAOBPDE4DSMN1; SMN2
SCHEMBL16167856 0.79 ACHE (0.45) ACHEMAOBPDE4DTP53ALKBH3
SCHEMBL25473944 0.77 PDK2 (0.47) ACHESMN1; SMN2ALDH1A1CA1CA2
SCHEMBL19286967 0.77 ACHE (0.48) ACHEMAOBPDE4DALDH1A1CYP3A4
SCHEMBL12830690 0.76 ACHE (0.42) ACHEMAOBPDE4DTP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9331284-B2 Polymer compound and light-emitting device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-03 US disclosed
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-12-27 US disclosed
US-20110187266-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CCNA1, CCNB1, CCNL2 ACHE 2098/4885KDM1A 708/4885MAOB 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.