Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374656 | 0.89 | LMNA (0.53) | ABCG2LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL2278626 | 0.87 | ACMSD (0.49) | ABCG2LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL2278601 | 0.87 | ABCG2 (0.47) | ABCG2LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL2278624 | 0.87 | ACMSD (0.49) | ABCG2LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL2278603 | 0.87 | ABCG2 (0.47) | ABCG2LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL2281949 | 0.86 | ABCG2 (0.47) | ABCG2LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL2281943 | 0.86 | ABCG2 (0.47) | ABCG2LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL2279952 | 0.85 | ABCG2 (0.46) | ABCG2LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL2279958 | 0.85 | ABCG2 (0.48) | ABCG2LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL2279949 | 0.85 | ABCG2 (0.46) | ABCG2LMNAHTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989478-B2 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |