Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | SCN2B | O60939 | 4/20 | 0.41 |
| ▸ | SCN1A | P35498 | 4/20 | 0.41 |
| ▸ | SCN1B | Q07699 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2278495 | 0.86 | UNG (0.54) | HDAC3HDAC1SCN9ASCN3ASCN2B | |
| Styrene SCHEMBL8438571 | 0.81 | HDAC1 (0.51) | HDAC1SCN9ASCN3ASCN2BSCN1A | |
| SCHEMBL24527569 | 0.80 | HDAC8 (0.58) | HDAC3HDAC1TP53TDP1HDAC8 | |
| SCHEMBL8437454 | 0.80 | TAS1R3 (0.50) | HDAC1SCN9ASCN3ATDP1HDAC6 | |
| SCHEMBL2159159 | 0.77 | PKM (0.51) | HDAC1SCN9ASCN3ASCN2BSCN1A | |
| SCHEMBL280256 | 0.77 | HDAC8 (0.68) | SCN9ASCN2BSCN1ASCN1BTP53 | |
| SCHEMBL13331743 | 0.77 | KDM4E (0.65) | SCN9ASCN3AHDAC8HDAC6MRGPRX4 | |
| SCHEMBL15652743 | 0.76 | HPGD (0.51) | HDAC1TP53TDP1HDAC8HDAC6 | |
| SCHEMBL17682697 | 0.76 | SMN1; SMN2 (0.49) | HDAC3HDAC1TP53TDP1ALDH1A1 | |
| SCHEMBL12374693 | 0.76 | GRIN2D (0.46) | HDAC3HDAC1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989478-B2 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |