Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4520097 | 0.80 | PADI4 (0.40) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL4520101 | 0.80 | PADI4 (0.40) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL13818103 | 0.79 | PADI4 (0.40) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL13403294 | 0.77 | MEN1 (0.51) | ALDH1A1HPGDKDM4EHTTCYP1A2 | |
| SCHEMBL2277602 | 0.77 | LMNA (0.40) | ALDH1A1HPGDKDM4EHTTGLA | |
| SCHEMBL2277607 | 0.77 | LMNA (0.40) | ALDH1A1HPGDKDM4EHTTGLA | |
| SCHEMBL13403305 | 0.73 | KDM4E (0.50) | ALDH1A1HPGDKDM4EHSD17B10HTT | |
| SCHEMBL12374855 | 0.73 | MEN1 (0.48) | ALDH1A1HPGDKDM4ERAB9AMEN1 | |
| SCHEMBL13818097 | 0.72 | PADI4 (0.40) | ALDH1A1HPGDKDM4ECYP1A2CYP2C19 | |
| SCHEMBL2281362 | 0.72 | HPGD (0.57) | ALDH1A1HPGDKDM4EHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989478-B2 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |