Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374646 | 0.89 | PADI4 (0.44) | PADI4NPC1RAB9AGAAPPARG | |
| SCHEMBL24329076 | 0.78 | PADI4 (0.44) | PADI4GAAALDH1A1 | |
| SCHEMBL12374651 | 0.77 | PADI4 (0.65) | PADI4NPC1RAB9AGAAPPARG | |
| SCHEMBL12374649 | 0.76 | PADI4 (0.45) | PADI4NPC1RAB9AGAAPPARG | |
| SCHEMBL12374714 | 0.75 | PADI4 (0.47) | PADI4NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL15233104 | 0.75 | PADI4 (0.37) | PADI4NPC1RAB9AGAAPPARG | |
| SCHEMBL13403201 | 0.74 | PADI4 (0.39) | PADI4NPC1RAB9APPARGALDH1A1 | |
| SCHEMBL13403211 | 0.69 | PADI4 (0.37) | PADI4 | |
| SCHEMBL14514826 | 0.69 | PADI4 (0.50) | PADI4NPC1RAB9AGAAPPARG | |
| SCHEMBL31384761 | 0.68 | LDHA (0.43) | NPC1RAB9AGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989478-B2 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |