Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15233104 | 0.89 | PADI4 (0.37) | PADI4ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL13403211 | 0.86 | PADI4 (0.37) | PADI4 | |
| SCHEMBL12374646 | 0.79 | PADI4 (0.44) | PADI4ALDH1A1RAB9APPARGNPC1 | |
| SCHEMBL13403221 | 0.78 | RAB9A (0.49) | PADI4ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL13403218 | 0.78 | MEN1 (0.40) | PADI4ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL12374705 | 0.74 | PADI4 (0.45) | PADI4ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL12374649 | 0.71 | PADI4 (0.45) | PADI4ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL24329076 | 0.70 | PADI4 (0.44) | PADI4ALDH1A1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL12374651 | 0.70 | PADI4 (0.65) | PADI4ALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL12374714 | 0.69 | PADI4 (0.47) | PADI4ALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524729-B2 | Cinnamoyl derivatives and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-03 | — | — | US | disclosed |
| US-7691883-B2 | Cinnamoyl compound and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-06 | — | — | US | disclosed |
| US-20070265228-A1 | Cinnamoyl compound and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-11-15 | — | — | US | disclosed |
| US-20070123521-A1 | Cinnamoyl derivatives and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265228-A1 | Cinnamoyl compound and use of the same | NPC1, CES2, CYP51A1 | PADI4 3465/4885ALDH1A1 83/4885MEN1 876/4885 |
| US-20070123521-A1 | Cinnamoyl derivatives and use thereof | CES2, EBP, CPT1A | PADI4 2457/4885ALDH1A1 31/4885MEN1 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.